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Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site.
Howell KA, Qiu X, Brannan JM, Bryan C, Davidson E, Holtsberg FW, Wec AZ, Shulenin S, Biggins JE, Douglas R, Enterlein SG, Turner HL, Pallesen J, Murin CD, He S, Kroeker A, Vu H, Herbert AS, Fusco ML, Nyakatura EK, Lai JR, Keck ZY, Foung SKH, Saphire EO, Zeitlin L, Ward AB, Chandran K, Doranz BJ, Kobinger GP, Dye JM, Aman MJ. Howell KA, et al. Among authors: he s. Cell Rep. 2016 May 17;15(7):1514-1526. doi: 10.1016/j.celrep.2016.04.026. Epub 2016 May 5. Cell Rep. 2016. PMID: 27160900 Free PMC article.
Development and Characterization of a Guinea Pig-Adapted Sudan Virus.
Wong G, He S, Wei H, Kroeker A, Audet J, Leung A, Cutts T, Graham J, Kobasa D, Embury-Hyatt C, Kobinger GP, Qiu X. Wong G, et al. Among authors: he s. J Virol. 2015 Oct 21;90(1):392-9. doi: 10.1128/JVI.02331-15. Print 2016 Jan 1. J Virol. 2015. PMID: 26491156 Free PMC article.
Two-mAb cocktail protects macaques against the Makona variant of Ebola virus.
Qiu X, Audet J, Lv M, He S, Wong G, Wei H, Luo L, Fernando L, Kroeker A, Fausther Bovendo H, Bello A, Li F, Ye P, Jacobs M, Ippolito G, Saphire EO, Bi S, Shen B, Gao GF, Zeitlin L, Feng J, Zhang B, Kobinger GP. Qiu X, et al. Among authors: he s. Sci Transl Med. 2016 Mar 9;8(329):329ra33. doi: 10.1126/scitranslmed.aad9875. Sci Transl Med. 2016. PMID: 26962157 Free PMC article.
Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection.
Zheng X, Wong G, Zhao Y, Wang H, He S, Bi Y, Chen W, Jin H, Gai W, Chu D, Cao Z, Wang C, Fan Q, Chi H, Gao Y, Wang T, Feng N, Yan F, Huang G, Zheng Y, Li N, Li Y, Qian J, Zou Y, Kobinger G, Gao GF, Qiu X, Yang S, Xia X. Zheng X, et al. Among authors: he s. Sci Rep. 2016 Apr 12;6:24179. doi: 10.1038/srep24179. Sci Rep. 2016. PMID: 27067649 Free PMC article.
Potent neutralizing monoclonal antibodies against Ebola virus infection.
Zhang Q, Gui M, Niu X, He S, Wang R, Feng Y, Kroeker A, Zuo Y, Wang H, Wang Y, Li J, Li C, Shi Y, Shi X, Gao GF, Xiang Y, Qiu X, Chen L, Zhang L. Zhang Q, et al. Among authors: he s. Sci Rep. 2016 May 16;6:25856. doi: 10.1038/srep25856. Sci Rep. 2016. PMID: 27181584 Free PMC article.
Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques.
Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H, Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Günther S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G. Wong G, et al. Among authors: he s. J Infect Dis. 2016 Oct 15;214(suppl 3):S281-S289. doi: 10.1093/infdis/jiw267. Epub 2016 Sep 19. J Infect Dis. 2016. PMID: 27651412 Free PMC article.
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