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Effects of the antitumor drug OSI-906, a dual inhibitor of IGF-1 receptor and insulin receptor, on the glycemic control, β-cell functions, and β-cell proliferation in male mice.
Shirakawa J, Okuyama T, Yoshida E, Shimizu M, Horigome Y, Tuno T, Hayasaka M, Abe S, Fuse M, Togashi Y, Terauchi Y. Shirakawa J, et al. Among authors: okuyama t. Endocrinology. 2014 Jun;155(6):2102-11. doi: 10.1210/en.2013-2032. Epub 2014 Apr 8. Endocrinology. 2014. PMID: 24712877
DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid.
Shirakawa J, Okuyama T, Kyohara M, Yoshida E, Togashi Y, Tajima K, Yamazaki S, Kaji M, Koganei M, Sasaki H, Terauchi Y. Shirakawa J, et al. Among authors: okuyama t. Diabetol Metab Syndr. 2016 Mar 1;8:16. doi: 10.1186/s13098-016-0138-4. eCollection 2016. Diabetol Metab Syndr. 2016. PMID: 26937254 Free PMC article.
Signaling between pancreatic β cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation.
Inoue H, Shirakawa J, Togashi Y, Tajima K, Okuyama T, Kyohara M, Tanaka Y, Orime K, Saisho Y, Yamada T, Shibue K, Kulkarni RN, Terauchi Y. Inoue H, et al. Among authors: okuyama t. J Biol Chem. 2018 Apr 20;293(16):5934-5946. doi: 10.1074/jbc.M117.809228. Epub 2018 Mar 1. J Biol Chem. 2018. PMID: 29496993 Free PMC article.
Influence of Timing of Insulin Initiation on Long-term Glycemic Control in Japanese Patients with Type 2 Diabetes: A Retrospective Cohort Study.
Miyazaki T, Shirakawa J, Nagakura J, Shibuya M, Kyohara M, Okuyama T, Togashi Y, Nakamura A, Kondo Y, Satoh S, Nakajima S, Taguri M, Terauchi Y. Miyazaki T, et al. Among authors: okuyama t. Intern Med. 2019 Dec 1;58(23):3361-3367. doi: 10.2169/internalmedicine.3060-19. Epub 2019 Jul 22. Intern Med. 2019. PMID: 31327835 Free PMC article.
1,399 results