Blazer LL - Search Results

1

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase.

Blazer LL, Lima-Fernandes E, Gibson E, Eram MS, Loppnau P, Arrowsmith CH, Schapira M, Vedadi M. Blazer LL, et al. J Biol Chem. 2016 Jun 24;291(26):13509-19. doi: 10.1074/jbc.M116.721472. Epub 2016 Apr 29. J Biol Chem. 2016. PMID: 27129774 Free PMC article.

2

Discovery of a chemical probe for PRDM9.

Allali-Hassani A, Szewczyk MM, Ivanochko D, Organ SL, Bok J, Ho JSY, Gay FPH, Li F, Blazer L, Eram MS, Halabelian L, Dilworth D, Luciani GM, Lima-Fernandes E, Wu Q, Loppnau P, Palmer N, Talib SZA, Brown PJ, Schapira M, Kaldis P, O'Hagan RC, Guccione E, Barsyte-Lovejoy D, Arrowsmith CH, Sanders JM, Kattar SD, Bennett DJ, Nicholson B, Vedadi M. Allali-Hassani A, et al. Nat Commun. 2019 Dec 17;10(1):5759. doi: 10.1038/s41467-019-13652-x. Nat Commun. 2019. PMID: 31848333 Free PMC article.

3

Targeting human SET1/MLL family of proteins.

Vedadi M, Blazer L, Eram MS, Barsyte-Lovejoy D, Arrowsmith CH, Hajian T. Vedadi M, et al. Protein Sci. 2017 Apr;26(4):662-676. doi: 10.1002/pro.3129. Epub 2017 Mar 6. Protein Sci. 2017. PMID: 28160335 Free PMC article. Review.

4

Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1.

Luan Y, Blazer LL, Hu H, Hajian T, Zhang J, Wu H, Houliston S, Arrowsmith CH, Vedadi M, Zheng YG. Luan Y, et al. Among authors: blazer ll. Org Biomol Chem. 2016 Jan 14;14(2):631-638. doi: 10.1039/c5ob01794g. Org Biomol Chem. 2016. PMID: 26541578 Free PMC article.

5

A Suite of Biochemical Assays for Screening RNA Methyltransferase BCDIN3D.

Blazer LL, Li F, Kennedy S, Zheng YG, Arrowsmith CH, Vedadi M. Blazer LL, et al. SLAS Discov. 2017 Jan;22(1):32-39. doi: 10.1177/1087057116666276. Epub 2016 Sep 27. SLAS Discov. 2017. PMID: 27581605 Free article.

6

A phage-displayed single-chain Fab library optimized for rapid production of single-chain IgGs.

Hanna R, Cardarelli L, Patel N, Blazer LL, Adams JJ, Sidhu SS. Hanna R, et al. Among authors: blazer ll. Protein Sci. 2020 Oct;29(10):2075-2084. doi: 10.1002/pro.3931. Epub 2020 Sep 15. Protein Sci. 2020. PMID: 32803886 Free PMC article.

7

Use of flow cytometric methods to quantify protein-protein interactions.

Blazer LL, Roman DL, Muxlow MR, Neubig RR. Blazer LL, et al. Curr Protoc Cytom. 2010 Jan;Chapter 13:Unit 13.11.1-15. doi: 10.1002/0471142956.cy1311s51. Curr Protoc Cytom. 2010. PMID: 20069525 Free PMC article.

8

Regulators of G protein signaling proteins as targets for drug discovery.

Sjögren B, Blazer LL, Neubig RR. Sjögren B, et al. Among authors: blazer ll. Prog Mol Biol Transl Sci. 2010;91:81-119. doi: 10.1016/S1877-1173(10)91004-1. Prog Mol Biol Transl Sci. 2010. PMID: 20691960 Review.

9

Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.

Gallo E, Kelil A, Haughey M, Cazares-Olivera M, Yates BP, Zhang M, Wang NY, Blazer L, Carderelli L, Adams JJ, Kossiakoff AA, Wells JA, Xie W, Sidhu SS. Gallo E, et al. J Mol Biol. 2021 Jul 23;433(15):167090. doi: 10.1016/j.jmb.2021.167090. Epub 2021 Jun 4. J Mol Biol. 2021. PMID: 34090922

10

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.

Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS. Pavlovic Z, et al. Among authors: blazer ll. MAbs. 2018 Nov-Dec;10(8):1157-1167. doi: 10.1080/19420862.2018.1515565. Epub 2018 Sep 25. MAbs. 2018. PMID: 30183492 Free PMC article.

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