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Page 1
Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host.
Klemm EJ, Gkrania-Klotsas E, Hadfield J, Forbester JL, Harris SR, Hale C, Heath JN, Wileman T, Clare S, Kane L, Goulding D, Otto TD, Kay S, Doffinger R, Cooke FJ, Carmichael A, Lever AM, Parkhill J, MacLennan CA, Kumararatne D, Dougan G, Kingsley RA. Klemm EJ, et al. Among authors: heath jn. Nat Microbiol. 2016 Mar;1(3):15023. doi: 10.1038/nmicrobiol.2015.23. Epub 2016 Jan 25. Nat Microbiol. 2016. PMID: 27127642 Free PMC article.
Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host.
Klemm EJ, Gkrania-Klotsas E, Hadfield J, Forbester JL, Harris SR, Hale C, Heath JN, Wileman T, Clare S, Kane L, Goulding D, Otto TD, Kay S, Doffinger R, Cooke FJ, Carmichael A, Lever AM, Parkhill J, MacLennan CA, Kumararatne D, Dougan G, Kingsley RA. Klemm EJ, et al. Among authors: heath jn. Nat Microbiol. 2016 Jan 25;1:15023. doi: 10.1038/nmicrobiol.2015.23. Nat Microbiol. 2016. PMID: 27572160
Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313.
Ondari EM, Klemm EJ, Msefula CL, El Ghany MA, Heath JN, Pickard DJ, Barquist L, Dougan G, Kingsley RA, MacLennan CA. Ondari EM, et al. Among authors: heath jn. Wellcome Open Res. 2019 Apr 25;4:74. doi: 10.12688/wellcomeopenres.15059.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31231691 Free PMC article.
IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.
Zhang Y, Dominguez-Medina C, Cumley NJ, Heath JN, Essex SJ, Bobat S, Schager A, Goodall M, Kracker S, Buckley CD, May RC, Kingsley RA, MacLennan CA, López-Macías C, Cunningham AF, Toellner KM. Zhang Y, et al. Among authors: heath jn. J Immunol. 2017 Dec 15;199(12):4103-4109. doi: 10.4049/jimmunol.1700952. Epub 2017 Nov 10. J Immunol. 2017. PMID: 29127147 Free PMC article.
Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing.
Wells TJ, Whitters D, Sevastsyanovich YR, Heath JN, Pravin J, Goodall M, Browning DF, O'Shea MK, Cranston A, De Soyza A, Cunningham AF, MacLennan CA, Henderson IR, Stockley RA. Wells TJ, et al. Among authors: heath jn. J Exp Med. 2014 Aug 25;211(9):1893-904. doi: 10.1084/jem.20132444. Epub 2014 Aug 11. J Exp Med. 2014. PMID: 25113975 Free PMC article.
Identification of a common immune signature in murine and human systemic Salmonellosis.
Lee SJ, Liang L, Juarez S, Nanton MR, Gondwe EN, Msefula CL, Kayala MA, Necchi F, Heath JN, Hart P, Tsolis RM, Heyderman RS, MacLennan CA, Felgner PL, Davies DH, McSorley SJ. Lee SJ, et al. Among authors: heath jn. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4998-5003. doi: 10.1073/pnas.1111413109. Epub 2012 Feb 13. Proc Natl Acad Sci U S A. 2012. PMID: 22331879 Free PMC article.