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The cytoprotective role of the Keap1-Nrf2 pathway.
Baird L, Dinkova-Kostova AT. Baird L, et al. Arch Toxicol. 2011 Apr;85(4):241-72. doi: 10.1007/s00204-011-0674-5. Epub 2011 Mar 2. Arch Toxicol. 2011. PMID: 21365312 Review.
Synthesis and biological evaluation of biotin conjugates of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydro-phenanthrene-2,6-dicarbonitrile, an activator of the Keap1/Nrf2/ARE pathway, for the isolation of its protein targets.
Saito A, Higgins M, Zheng S, Li W, Ojima I, Dinkova-Kostova AT, Honda T. Saito A, et al. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5540-3. doi: 10.1016/j.bmcl.2013.08.058. Epub 2013 Aug 21. Bioorg Med Chem Lett. 2013. PMID: 24018193
Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.
Knatko EV, Ibbotson SH, Zhang Y, Higgins M, Fahey JW, Talalay P, Dawe RS, Ferguson J, Huang JT, Clarke R, Zheng S, Saito A, Kalra S, Benedict AL, Honda T, Proby CM, Dinkova-Kostova AT. Knatko EV, et al. Cancer Prev Res (Phila). 2015 Jun;8(6):475-86. doi: 10.1158/1940-6207.CAPR-14-0362. Epub 2015 Mar 24. Cancer Prev Res (Phila). 2015. PMID: 25804610 Free PMC article.
194 results