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987 results

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Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes, in particular in redox and energy metabolism.
Soriano GP, Besse L, Li N, Kraus M, Besse A, Meeuwenoord N, Bader J, Everts B, den Dulk H, Overkleeft HS, Florea BI, Driessen C. Soriano GP, et al. Among authors: bader j. Leukemia. 2016 Nov;30(11):2198-2207. doi: 10.1038/leu.2016.102. Epub 2016 Apr 27. Leukemia. 2016. PMID: 27118406 Free PMC article.
The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells.
Kraus M, Bader J, Geurink PP, Weyburne ES, Mirabella AC, Silzle T, Shabaneh TB, van der Linden WA, de Bruin G, Haile SR, van Rooden E, Appenzeller C, Li N, Kisselev AF, Overkleeft H, Driessen C. Kraus M, et al. Among authors: bader j. Haematologica. 2015 Oct;100(10):1350-60. doi: 10.3324/haematol.2014.109421. Epub 2015 Jun 11. Haematologica. 2015. PMID: 26069288 Free PMC article.
Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus (HIV)-protease inhibitors lopinavir or nelfinavir.
Abt D, Besse A, Sedlarikova L, Kraus M, Bader J, Silzle T, Vodinska M, Slaby O, Schmid HP, Engeler DS, Driessen C, Besse L. Abt D, et al. Among authors: bader j. BJU Int. 2018 Apr;121(4):600-609. doi: 10.1111/bju.14083. Epub 2017 Dec 10. BJU Int. 2018. PMID: 29161753
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome.
Goold HD, Kroukamp H, Erpf PE, Zhao Y, Kelso P, Calame J, Timmins JJB, Wightman ELI, Peng K, Carpenter AC, Llorente B, Hawthorne C, Clay S, van Wyk N, Daniel EL, Harrison F, Meier F, Willows RD, Cai Y, Walker RSK, Xu X, Espinosa MI, Stracquadanio G, Bader JS, Mitchell LA, Boeke JD, Williams TC, Paulsen IT, Pretorius IS. Goold HD, et al. Among authors: bader js. Nat Commun. 2025 Jan 20;16(1):841. doi: 10.1038/s41467-024-55318-3. Nat Commun. 2025. PMID: 39833175 Free PMC article.
Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure.
Peterson TE, Hahn VS, Moaddel R, Zhu M, Haberlen SA, Palella FJ, Plankey M, Bader JS, Lima JAC, Gerszten RE, Rotter JI, Rich SS, Heckbert SR, Kirk GD, Piggott DA, Ferrucci L, Margolick JB, Brown TT, Wu KC, Post WS. Peterson TE, et al. Among authors: bader js. Nat Commun. 2025 Jan 12;16(1):610. doi: 10.1038/s41467-025-55911-0. Nat Commun. 2025. PMID: 39800750 Free PMC article.
987 results