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Mutual A domain interactions in the force sensing protein von Willebrand factor.
Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm MA, Gruber HJ, Netz RR, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P. Posch S, et al. Among authors: grater f. J Struct Biol. 2017 Jan;197(1):57-64. doi: 10.1016/j.jsb.2016.04.012. Epub 2016 Apr 23. J Struct Biol. 2017. PMID: 27113902 Free article.
Collagen breaks at weak sacrificial bonds taming its mechanoradicals.
Rennekamp B, Karfusehr C, Kurth M, Ünal A, Monego D, Riedmiller K, Gryn'ova G, Hudson DM, Gräter F. Rennekamp B, et al. Among authors: grater f. Nat Commun. 2023 Apr 12;14(1):2075. doi: 10.1038/s41467-023-37726-z. Nat Commun. 2023. PMID: 37045839 Free PMC article.
Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis.
Baldauf C, Schneppenheim R, Stacklies W, Obser T, Pieconka A, Schneppenheim S, Budde U, Zhou J, Gräter F. Baldauf C, et al. Among authors: grater f. J Thromb Haemost. 2009 Dec;7(12):2096-105. doi: 10.1111/j.1538-7836.2009.03640.x. Epub 2009 Oct 8. J Thromb Haemost. 2009. PMID: 19817991 Free article.
133 results