Lees JA - Search Results

1

STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.

Guen VJ, Gamble C, Perez DE, Bourassa S, Zappel H, Gärtner J, Lees JA, Colas P. Guen VJ, et al. Among authors: lees ja. Cell Cycle. 2016;15(5):678-88. doi: 10.1080/15384101.2016.1147632. Cell Cycle. 2016. PMID: 27104747 Free PMC article.

2

E2F3 plays an essential role in cardiac development and function.

King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA. King JC, et al. Among authors: lees ja. Cell Cycle. 2008 Dec;7(23):3775-80. doi: 10.4161/cc.7.23.7240. Epub 2008 Dec 22. Cell Cycle. 2008. PMID: 19029823 Free PMC article.

3

Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations.

Miller ES, Berman SD, Yuan TL, Lees JA. Miller ES, et al. Among authors: lees ja. Cell Cycle. 2010 Jul 1;9(13):2620-8. doi: 10.4161/cc.9.13.12108. Cell Cycle. 2010. PMID: 20581455 Free PMC article.

4

E2f4 and E2f5 are essential for the development of the male reproductive system.

Danielian PS, Hess RA, Lees JA. Danielian PS, et al. Among authors: lees ja. Cell Cycle. 2016;15(2):250-60. doi: 10.1080/15384101.2015.1121350. Cell Cycle. 2016. PMID: 26825228 Free PMC article.

5

The awakening of the CDK10/Cyclin M protein kinase.

Guen VJ, Gamble C, Lees JA, Colas P. Guen VJ, et al. Among authors: lees ja. Oncotarget. 2017 Jul 25;8(30):50174-50186. doi: 10.18632/oncotarget.15024. Oncotarget. 2017. PMID: 28178678 Free PMC article. Review.

6

A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness.

Guen VJ, Edvardson S, Fraenkel ND, Fattal-Valevski A, Jalas C, Anteby I, Shaag A, Dor T, Gillis D, Kerem E, Lees JA, Colas P, Elpeleg O. Guen VJ, et al. Among authors: lees ja. Am J Med Genet A. 2018 Jan;176(1):92-98. doi: 10.1002/ajmg.a.38506. Epub 2017 Nov 12. Am J Med Genet A. 2018. PMID: 29130579 Free PMC article.

7

EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.

Guen VJ, Chavarria TE, Kröger C, Ye X, Weinberg RA, Lees JA. Guen VJ, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10532-E10539. doi: 10.1073/pnas.1711534114. Epub 2017 Nov 20. Proc Natl Acad Sci U S A. 2017. PMID: 29158396 Free PMC article.

8

Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.

Perez DE, Henle AM, Amsterdam A, Hagen HR, Lees JA. Perez DE, et al. Among authors: lees ja. Pigment Cell Melanoma Res. 2018 Sep;31(5):604-613. doi: 10.1111/pcmr.12700. Epub 2018 Apr 6. Pigment Cell Melanoma Res. 2018. PMID: 29570931 Free PMC article.

9

Emerging Mechanisms by which EMT Programs Control Stemness.

Wilson MM, Weinberg RA, Lees JA, Guen VJ. Wilson MM, et al. Among authors: lees ja. Trends Cancer. 2020 Sep;6(9):775-780. doi: 10.1016/j.trecan.2020.03.011. Epub 2020 Apr 17. Trends Cancer. 2020. PMID: 32312682 Free article. Review.

10

E2F4's cytoplasmic role in multiciliogenesis is mediated via an N-terminal domain that binds two components of the centriole replication machinery, Deup1 and SAS6.

Hazan R, Mori M, Danielian PS, Guen VJ, Rubin SM, Cardoso WV, Lees JA. Hazan R, et al. Among authors: lees ja. Mol Biol Cell. 2021 Oct 1;32(20):ar1. doi: 10.1091/mbc.E21-01-0039. Epub 2021 Jul 14. Mol Biol Cell. 2021. PMID: 34260288 Free PMC article.

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