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551 results

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Page 1
A research roadmap for next-generation sequencing informatics.
Altman RB, Prabhu S, Sidow A, Zook JM, Goldfeder R, Litwack D, Ashley E, Asimenos G, Bustamante CD, Donigan K, Giacomini KM, Johansen E, Khuri N, Lee E, Liang XS, Salit M, Serang O, Tezak Z, Wall DP, Mansfield E, Kass-Hout T. Altman RB, et al. Sci Transl Med. 2016 Apr 20;8(335):335ps10. doi: 10.1126/scitranslmed.aaf7314. Sci Transl Med. 2016. PMID: 27099173 Free PMC article. Review.
A general framework for dose optimization.
Turcott RG, Sagreiya H, Ashley EA, Altman RB, Das AK. Turcott RG, et al. Among authors: altman rb. AMIA Annu Symp Proc. 2009 Nov 14;2009:656-60. AMIA Annu Symp Proc. 2009. PMID: 20351936 Free PMC article.
Challenges in the clinical application of whole-genome sequencing.
Ormond KE, Wheeler MT, Hudgins L, Klein TE, Butte AJ, Altman RB, Ashley EA, Greely HT. Ormond KE, et al. Among authors: altman rb. Lancet. 2010 May 15;375(9727):1749-51. doi: 10.1016/S0140-6736(10)60599-5. Epub 2010 Apr 29. Lancet. 2010. PMID: 20434765 No abstract available.
SLC19A1 pharmacogenomics summary.
Yee SW, Gong L, Badagnani I, Giacomini KM, Klein TE, Altman RB. Yee SW, et al. Among authors: altman rb. Pharmacogenet Genomics. 2010 Nov;20(11):708-15. doi: 10.1097/FPC.0b013e32833eca92. Pharmacogenet Genomics. 2010. PMID: 20811316 Free PMC article. No abstract available.
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence.
Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA. Dewey FE, et al. Among authors: altman rb. PLoS Genet. 2011 Sep;7(9):e1002280. doi: 10.1371/journal.pgen.1002280. Epub 2011 Sep 15. PLoS Genet. 2011. PMID: 21935354 Free PMC article.
Metformin pathways: pharmacokinetics and pharmacodynamics.
Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE. Gong L, et al. Among authors: altman rb. Pharmacogenet Genomics. 2012 Nov;22(11):820-7. doi: 10.1097/FPC.0b013e3283559b22. Pharmacogenet Genomics. 2012. PMID: 22722338 Free PMC article. Review. No abstract available.
Informatics confronts drug-drug interactions.
Percha B, Altman RB. Percha B, et al. Among authors: altman rb. Trends Pharmacol Sci. 2013 Mar;34(3):178-84. doi: 10.1016/j.tips.2013.01.006. Epub 2013 Feb 13. Trends Pharmacol Sci. 2013. PMID: 23414686 Free PMC article. Review.
Clinical interpretation and implications of whole-genome sequencing.
Dewey FE, Grove ME, Pan C, Goldstein BA, Bernstein JA, Chaib H, Merker JD, Goldfeder RL, Enns GM, David SP, Pakdaman N, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carrillo M, Sakamoto K, Wheeler MT, Butte AJ, Ford JM, Boxer L, Ioannidis JP, Yeung AC, Altman RB, Assimes TL, Snyder M, Ashley EA, Quertermous T. Dewey FE, et al. Among authors: altman rb. JAMA. 2014 Mar 12;311(10):1035-45. doi: 10.1001/jama.2014.1717. JAMA. 2014. PMID: 24618965 Free PMC article.
PharmGKB summary: very important pharmacogene information for SLC22A1.
Goswami S, Gong L, Giacomini K, Altman RB, Klein TE. Goswami S, et al. Among authors: altman rb. Pharmacogenet Genomics. 2014 Jun;24(6):324-8. doi: 10.1097/FPC.0000000000000048. Pharmacogenet Genomics. 2014. PMID: 24681965 Free PMC article. No abstract available.
551 results