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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Keune WJ, et al. Among authors: morris aj. Nat Commun. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248. Nat Commun. 2016. PMID: 27075612 Free PMC article.
Therapeutic potential of autotaxin/lysophospholipase d inhibitors.
Federico L, Pamuklar Z, Smyth SS, Morris AJ. Federico L, et al. Among authors: morris aj. Curr Drug Targets. 2008 Aug;9(8):698-708. doi: 10.2174/138945008785132439. Curr Drug Targets. 2008. PMID: 18691016 Free PMC article. Review.
Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.
Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, Smyth SS. Pamuklar Z, et al. Among authors: morris aj. J Biol Chem. 2009 Mar 13;284(11):7385-94. doi: 10.1074/jbc.M807820200. Epub 2009 Jan 12. J Biol Chem. 2009. PMID: 19139100 Free PMC article.
Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells.
Miriyala S, Subramanian T, Panchatcharam M, Ren H, McDermott MI, Sunkara M, Drennan T, Smyth SS, Spielmann HP, Morris AJ. Miriyala S, et al. Among authors: morris aj. J Biol Chem. 2010 Apr 30;285(18):13918-29. doi: 10.1074/jbc.M109.083931. Epub 2010 Jan 28. J Biol Chem. 2010. PMID: 20110354 Free PMC article.
Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.
Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Albers HM, et al. Among authors: morris aj. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7257-62. doi: 10.1073/pnas.1001529107. Epub 2010 Apr 1. Proc Natl Acad Sci U S A. 2010. PMID: 20360563 Free PMC article.
797 results