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Page 1
Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing.
Lecomte E, Tournaire B, Cogné B, Dupont JB, Lindenbaum P, Martin-Fontaine M, Broucque F, Robin C, Hebben M, Merten OW, Blouin V, François A, Redon R, Moullier P, Léger A. Lecomte E, et al. Among authors: broucque f. Mol Ther Nucleic Acids. 2015 Oct 27;4(10):e260. doi: 10.1038/mtna.2015.32. Mol Ther Nucleic Acids. 2015. PMID: 26506038 Free PMC article.
AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations.
Pacouret S, Bouzelha M, Shelke R, Andres-Mateos E, Xiao R, Maurer A, Mevel M, Turunen H, Barungi T, Penaud-Budloo M, Broucque F, Blouin V, Moullier P, Ayuso E, Vandenberghe LH. Pacouret S, et al. Among authors: broucque f. Mol Ther. 2017 Jun 7;25(6):1375-1386. doi: 10.1016/j.ymthe.2017.04.001. Epub 2017 Apr 17. Mol Ther. 2017. PMID: 28427840 Free PMC article.
Stability of the adeno-associated virus 8 reference standard material.
Penaud-Budloo M, Broucque F, Harrouet K, Bouzelha M, Saleun S, Douthe S, D'Costa S, Ogram S, Adjali O, Blouin V, Lock M, Snyder RO, Ayuso E. Penaud-Budloo M, et al. Among authors: broucque f. Gene Ther. 2019 May;26(5):211-215. doi: 10.1038/s41434-019-0072-9. Epub 2019 Mar 29. Gene Ther. 2019. PMID: 30926961
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries.
Schmit PF, Pacouret S, Zinn E, Telford E, Nicolaou F, Broucque F, Andres-Mateos E, Xiao R, Penaud-Budloo M, Bouzelha M, Jaulin N, Adjali O, Ayuso E, Vandenberghe LH. Schmit PF, et al. Among authors: broucque f. Mol Ther Methods Clin Dev. 2019 Nov 26;17:107-121. doi: 10.1016/j.omtm.2019.11.014. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31909084 Free PMC article.
Homologous Recombination Offers Advantages over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.
Jacob A, Brun L, Jiménez Gil P, Ménard L, Bouzelha M, Broucque F, Roblin A, Vandenberghe LH, Adjali O, Robin C, François A, Blouin V, Penaud-Budloo M, Ayuso E. Jacob A, et al. Among authors: broucque f. Biotechnol J. 2021 Jan;16(1):e2000014. doi: 10.1002/biot.202000014. Epub 2020 Nov 16. Biotechnol J. 2021. PMID: 33067902
Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells.
Penaud-Budloo M, Lecomte E, Lecomte Q, Pacouret S, Broucque F, Guy-Duché A, Dupont JB, Jeanson-Leh L, Robin C, Blouin V, Ayuso E, Adjali O. Penaud-Budloo M, et al. Among authors: broucque f. Mol Ther Methods Clin Dev. 2024 Jul 25;32(3):101305. doi: 10.1016/j.omtm.2024.101305. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39220637 Free PMC article.