Schreiber SL - Search Results

1

Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile.

Boskovic ZV, Kemp MM, Freedy AM, Viswanathan VS, Pop MS, Fuller JH, Martinez NM, Figueroa Lazú SO, Hong JA, Lewis TA, Calarese D, Love JD, Vetere A, Almo SC, Schreiber SL, Koehler AN. Boskovic ZV, et al. Among authors: schreiber sl. ACS Chem Biol. 2016 Jul 15;11(7):1844-51. doi: 10.1021/acschembio.6b00012. Epub 2016 Apr 29. ACS Chem Biol. 2016. PMID: 27064299

2

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

Hassig CA, Schreiber SL. Hassig CA, et al. Among authors: schreiber sl. Curr Opin Chem Biol. 1997 Oct;1(3):300-8. doi: 10.1016/s1367-5931(97)80066-x. Curr Opin Chem Biol. 1997. PMID: 9667866 Review.

3

Three proteins define a class of human histone deacetylases related to yeast Hda1p.

Grozinger CM, Hassig CA, Schreiber SL. Grozinger CM, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4868-73. doi: 10.1073/pnas.96.9.4868. Proc Natl Acad Sci U S A. 1999. PMID: 10220385 Free PMC article.

4

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening.

Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL. Grozinger CM, et al. Among authors: schreiber sl. J Biol Chem. 2001 Oct 19;276(42):38837-43. doi: 10.1074/jbc.M106779200. Epub 2001 Aug 1. J Biol Chem. 2001. PMID: 11483616 Free article.

5

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

6

Structural biasing elements for in-cell histone deacetylase paralog selectivity.

Wong JC, Hong R, Schreiber SL. Wong JC, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 May 14;125(19):5586-7. doi: 10.1021/ja0341440. J Am Chem Soc. 2003. PMID: 12733869

7

Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation.

Koeller KM, Haggarty SJ, Perkins BD, Leykin I, Wong JC, Kao MC, Schreiber SL. Koeller KM, et al. Among authors: schreiber sl. Chem Biol. 2003 May;10(5):397-410. doi: 10.1016/s1074-5521(03)00093-0. Chem Biol. 2003. PMID: 12770822

8

Expanding the functional group compatibility of small-molecule microarrays: discovery of novel calmodulin ligands.

Barnes-Seeman D, Park SB, Koehler AN, Schreiber SL. Barnes-Seeman D, et al. Among authors: schreiber sl. Angew Chem Int Ed Engl. 2003 May 30;42(21):2376-9. doi: 10.1002/anie.200351043. Angew Chem Int Ed Engl. 2003. PMID: 12783500 No abstract available.

9

Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.

Koehler AN, Shamji AF, Schreiber SL. Koehler AN, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Jul 16;125(28):8420-1. doi: 10.1021/ja0352698. J Am Chem Soc. 2003. PMID: 12848532

10

A robust small-molecule microarray platform for screening cell lysates.

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN. Bradner JE, et al. Among authors: schreiber sl. Chem Biol. 2006 May;13(5):493-504. doi: 10.1016/j.chembiol.2006.03.004. Chem Biol. 2006. PMID: 16720270

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