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Interleukin-18-deficient mice develop dyslipidemia resulting in nonalcoholic fatty liver disease and steatohepatitis.
Yamanishi K, Maeda S, Kuwahara-Otani S, Watanabe Y, Yoshida M, Ikubo K, Okuzaki D, El-Darawish Y, Li W, Nakasho K, Nojima H, Yamanishi H, Hayakawa T, Okamura H, Matsunaga H. Yamanishi K, et al. Among authors: nakasho k. Transl Res. 2016 Jul;173:101-114.e7. doi: 10.1016/j.trsl.2016.03.010. Epub 2016 Mar 19. Transl Res. 2016. PMID: 27063959
Physiological and molecular effects of interleukin-18 administration on the mouse kidney.
Yamanishi K, Mukai K, Hashimoto T, Ikubo K, Nakasho K, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Hayakawa T, Nojima H, Yamanishi H, Okamura H, Matsunaga H. Yamanishi K, et al. Among authors: nakasho k. J Transl Med. 2018 Mar 7;16(1):51. doi: 10.1186/s12967-018-1426-6. J Transl Med. 2018. PMID: 29514661 Free PMC article.
Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia.
Yamanishi K, Maeda S, Kuwahara-Otani S, Hashimoto T, Ikubo K, Mukai K, Nakasho K, Gamachi N, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Yamanishi H, Okamura H, Matsunaga H. Yamanishi K, et al. Among authors: nakasho k. J Transl Med. 2018 Nov 19;16(1):314. doi: 10.1186/s12967-018-1684-3. J Transl Med. 2018. PMID: 30453990 Free PMC article.
Effect of interleukin-18 on metastasis of mouse osteosarcoma cells.
Nakamura Y, Yamada N, Ohyama H, Nakasho K, Nishizawa Y, Okamoto T, Futani H, Yoshiya S, Okamura H, Terada N. Nakamura Y, et al. Among authors: nakasho k. Cancer Immunol Immunother. 2006 Sep;55(9):1151-8. doi: 10.1007/s00262-005-0097-3. Epub 2006 Jan 12. Cancer Immunol Immunother. 2006. PMID: 16408211 Free PMC article.
Enhanced suppression of pulmonary metastasis of malignant melanoma cells by combined administration of alpha-galactosylceramide and interleukin-18.
Nishio S, Yamada N, Ohyama H, Yamanegi K, Nakasho K, Hata M, Nakamura Y, Fukunaga S, Futani H, Yoshiya S, Ueda H, Taniguchi M, Okamura H, Terada N. Nishio S, et al. Among authors: nakasho k. Cancer Sci. 2008 Jan;99(1):113-20. doi: 10.1111/j.1349-7006.2007.00636.x. Epub 2007 Oct 18. Cancer Sci. 2008. PMID: 17949451 Free PMC article.
Sodium valproate, a histone deacetylase inhibitor, decreases the secretion of soluble Fas by human osteosarcoma cells and increases their sensitivity to Fas-mediated cell death.
Yamanegi K, Yamane J, Hata M, Ohyama H, Yamada N, Kato-Kogoe N, Futani H, Nakasho K, Okamura H, Terada N. Yamanegi K, et al. Among authors: nakasho k. J Cancer Res Clin Oncol. 2009 Jul;135(7):879-89. doi: 10.1007/s00432-008-0522-z. Epub 2008 Dec 9. J Cancer Res Clin Oncol. 2009. PMID: 19066961
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