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The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders.
Kibitov AA, Kiryanova EM, Salnikova LI, Bure IV, Shmukler AB, Kibitov AO. Kibitov AA, et al. Among authors: kiryanova em. Drug Metab Pers Ther. 2022 Nov 28;38(2):133-142. doi: 10.1515/dmpt-2022-0143. eCollection 2023 Jun 1. Drug Metab Pers Ther. 2022. PMID: 36437548