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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Among authors: gustafsson ja. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.
Endo-Umeda K, Kim E, Thomas DG, Liu W, Dou H, Yalcinkaya M, Abramowicz S, Xiao T, Antonson P, Gustafsson JÅ, Makishima M, Reilly MP, Wang N, Tall AR. Endo-Umeda K, et al. Among authors: gustafsson ja. Arterioscler Thromb Vasc Biol. 2022 Jun;42(6):719-731. doi: 10.1161/ATVBAHA.122.317583. Epub 2022 Apr 28. Arterioscler Thromb Vasc Biol. 2022. PMID: 35477277 Free PMC article.
On the regulatory importance of 27-hydroxycholesterol in mouse liver.
Heverin M, Ali Z, Olin M, Tillander V, Joibari MM, Makoveichuk E, Leitersdorf E, Warner M, Olivercrona G, Gustafsson JÅ, Björkhem I. Heverin M, et al. Among authors: gustafsson ja. J Steroid Biochem Mol Biol. 2017 May;169:10-21. doi: 10.1016/j.jsbmb.2016.02.001. Epub 2016 Feb 3. J Steroid Biochem Mol Biol. 2017. PMID: 26851362
Liver X receptors are required for thymic resilience and T cell output.
Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK. Chan CT, et al. Among authors: gustafsson ja. J Exp Med. 2020 Oct 5;217(10):e20200318. doi: 10.1084/jem.20200318. J Exp Med. 2020. PMID: 32716519 Free PMC article.
mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5.
Hauser S, Poenisch M, Schelling Y, Höflinger P, Schuster S, Teegler A, Betten R, Gustafsson JÅ, Hübener-Schmid J, Schlake T, Chevessier-Tünnesen F, Horscroft N, Björkhem I, Schöls L. Hauser S, et al. Among authors: gustafsson ja. Mol Ther Methods Clin Dev. 2019 Oct 31;15:359-370. doi: 10.1016/j.omtm.2019.10.011. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31828178 Free PMC article.
Targeting liver X receptors in cancer therapeutics.
Lin CY, Gustafsson JÅ. Lin CY, et al. Among authors: gustafsson ja. Nat Rev Cancer. 2015 Apr;15(4):216-24. doi: 10.1038/nrc3912. Epub 2015 Mar 19. Nat Rev Cancer. 2015. PMID: 25786697 Review.
1,477 results