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p66Shc-dependent apoptosis requires Lck and CamKII activity.
Patrussi L, Giommoni N, Pellegrini M, Gamberucci A, Baldari CT. Patrussi L, et al. Among authors: baldari ct. Apoptosis. 2012 Feb;17(2):174-86. doi: 10.1007/s10495-011-0663-4. Apoptosis. 2012. PMID: 21983898
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes.
Patrussi L, Capitani N, Cattaneo F, Manganaro N, Gamberucci A, Frezzato F, Martini V, Visentin A, Pelicci PG, D'Elios MM, Trentin L, Semenzato G, Baldari CT. Patrussi L, et al. Among authors: baldari ct. Oncogene. 2018 Mar;37(11):1534-1550. doi: 10.1038/s41388-017-0066-2. Epub 2018 Jan 12. Oncogene. 2018. PMID: 29326436 Clinical Trial.
245 results