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Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance.
Nishimoto S, Fukuda D, Higashikuni Y, Tanaka K, Hirata Y, Murata C, Kim-Kaneyama JR, Sato F, Bando M, Yagi S, Soeki T, Hayashi T, Imoto I, Sakaue H, Shimabukuro M, Sata M. Nishimoto S, et al. Among authors: sakaue h. Sci Adv. 2016 Mar 25;2(3):e1501332. doi: 10.1126/sciadv.1501332. eCollection 2016 Mar. Sci Adv. 2016. PMID: 27051864 Free PMC article.
Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy.
Yasue S, Masuzaki H, Okada S, Ishii T, Kozuka C, Tanaka T, Fujikura J, Ebihara K, Hosoda K, Katsurada A, Ohashi N, Urushihara M, Kobori H, Morimoto N, Kawazoe T, Naitoh M, Okada M, Sakaue H, Suzuki S, Nakao K. Yasue S, et al. Among authors: sakaue h. Am J Hypertens. 2010 Apr;23(4):425-31. doi: 10.1038/ajh.2009.263. Epub 2010 Jan 7. Am J Hypertens. 2010. PMID: 20057360 Free PMC article.
Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion.
Nagare T, Sakaue H, Matsumoto M, Cao Y, Inagaki K, Sakai M, Takashima Y, Nakamura K, Mori T, Okada Y, Matsuki Y, Watanabe E, Ikeda K, Taguchi R, Kamimura N, Ohta S, Hiramatsu R, Kasuga M. Nagare T, et al. Among authors: sakaue h. J Biol Chem. 2011 Oct 28;286(43):37458-69. doi: 10.1074/jbc.M111.242651. Epub 2011 Aug 23. J Biol Chem. 2011. PMID: 21862590 Free PMC article.
Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like peptide-1 secretion and reduces adipose tissue inflammation.
Kihira Y, Miyake M, Hirata M, Hoshina Y, Kato K, Shirakawa H, Sakaue H, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T, Tomita S. Kihira Y, et al. Among authors: sakaue h. PLoS One. 2014 Apr 4;9(4):e93856. doi: 10.1371/journal.pone.0093856. eCollection 2014. PLoS One. 2014. PMID: 24705496 Free PMC article.
238 results