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Maize centromere structure and evolution: sequence analysis of centromeres 2 and 5 reveals dynamic Loci shaped primarily by retrotransposons.
Wolfgruber TK, Sharma A, Schneider KL, Albert PS, Koo DH, Shi J, Gao Z, Han F, Lee H, Xu R, Allison J, Birchler JA, Jiang J, Dawe RK, Presting GG. Wolfgruber TK, et al. Among authors: xu r. PLoS Genet. 2009 Nov;5(11):e1000743. doi: 10.1371/journal.pgen.1000743. Epub 2009 Nov 20. PLoS Genet. 2009. PMID: 19956743 Free PMC article.
BAP1 is a novel regulator of HIF-1α.
Bononi A, Wang Q, Zolondick AA, Bai F, Steele-Tanji M, Suarez JS, Pastorino S, Sipes A, Signorato V, Ferro A, Novelli F, Kim JH, Minaai M, Takinishi Y, Pellegrini L, Napolitano A, Xu R, Farrar C, Goparaju C, Bassi C, Negrini M, Pagano I, Sakamoto G, Gaudino G, Pass HI, Onuchic JN, Yang H, Carbone M. Bononi A, et al. Among authors: xu r. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217840120. doi: 10.1073/pnas.2217840120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656861 Free PMC article.
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma.
Suarez JS, Novelli F, Goto K, Ehara M, Steele M, Kim JH, Zolondick AA, Xue J, Xu R, Saito M, Pastorino S, Minaai M, Takanishi Y, Emi M, Pagano I, Wakeham A, Berger T, Pass HI, Gaudino G, Mak TW, Carbone M, Yang H. Suarez JS, et al. Among authors: xu r. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2307999120. doi: 10.1073/pnas.2307999120. Epub 2023 Sep 20. Proc Natl Acad Sci U S A. 2023. PMID: 37729199 Free PMC article.
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy.
Xue J, Patergnani S, Giorgi C, Suarez J, Goto K, Bononi A, Tanji M, Novelli F, Pastorino S, Xu R, Caroccia N, Dogan AU, Pass HI, Tognon M, Pinton P, Gaudino G, Mak TW, Carbone M, Yang H. Xue J, et al. Among authors: xu r. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25543-25552. doi: 10.1073/pnas.2007622117. Epub 2020 Sep 30. Proc Natl Acad Sci U S A. 2020. PMID: 32999071 Free PMC article.
Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling.
Novelli F, Yoshikawa Y, Vitto VAM, Modesti L, Minaai M, Pastorino S, Emi M, Kim JH, Kricek F, Bai F, Onuchic JN, Bononi A, Suarez JS, Tanji M, Favaron C, Zolondick AA, Xu R, Takanishi Y, Wang Z, Sakamoto G, Gaudino G, Grzymski J, Grosso F, Schrump DS, Pass HI, Atanesyan L, Smout J, Savola S, Sarin KY, Abolhassani H, Hammarström L, Pan-Hammarström Q, Giorgi C, Pinton P, Yang H, Carbone M. Novelli F, et al. Among authors: xu r. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2405231121. doi: 10.1073/pnas.2405231121. Epub 2024 Jul 11. Proc Natl Acad Sci U S A. 2024. PMID: 38990952 Free PMC article.
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.
Bononi A, Goto K, Ak G, Yoshikawa Y, Emi M, Pastorino S, Carparelli L, Ferro A, Nasu M, Kim JH, Suarez JS, Xu R, Tanji M, Takinishi Y, Minaai M, Novelli F, Pagano I, Gaudino G, Pass HI, Groden J, Grzymski JJ, Metintas M, Akarsu M, Morrow B, Hassan R, Yang H, Carbone M. Bononi A, et al. Among authors: xu r. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33466-33473. doi: 10.1073/pnas.2019652117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318203 Free PMC article.
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