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The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.
Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, Pedra JHF. Wang X, et al. Among authors: kotsyfakis m. Infect Immun. 2016 May 24;84(6):1796-1805. doi: 10.1128/IAI.01526-15. Print 2016 Jun. Infect Immun. 2016. PMID: 27045038 Free PMC article.
Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
Calvo E, Mizurini DM, Sá-Nunes A, Ribeiro JM, Andersen JF, Mans BJ, Monteiro RQ, Kotsyfakis M, Francischetti IM. Calvo E, et al. Among authors: kotsyfakis m. J Biol Chem. 2011 Aug 12;286(32):27998-8010. doi: 10.1074/jbc.M111.247924. Epub 2011 Jun 14. J Biol Chem. 2011. PMID: 21673107 Free PMC article.
Tick salivary secretion as a source of antihemostatics.
Chmelar J, Calvo E, Pedra JH, Francischetti IM, Kotsyfakis M. Chmelar J, et al. Among authors: kotsyfakis m. J Proteomics. 2012 Jul 16;75(13):3842-54. doi: 10.1016/j.jprot.2012.04.026. Epub 2012 Apr 27. J Proteomics. 2012. PMID: 22564820 Free PMC article. Review.
The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.
Chen G, Wang X, Severo MS, Sakhon OS, Sohail M, Brown LJ, Sircar M, Snyder GA, Sundberg EJ, Ulland TK, Olivier AK, Andersen JF, Zhou Y, Shi GP, Sutterwala FS, Kotsyfakis M, Pedra JH. Chen G, et al. Among authors: kotsyfakis m. Infect Immun. 2014 Jun;82(6):2553-64. doi: 10.1128/IAI.01679-14. Epub 2014 Mar 31. Infect Immun. 2014. PMID: 24686067 Free PMC article.
93 results