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TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis.
Sakamuri SS, Valente AJ, Siddesha JM, Delafontaine P, Siebenlist U, Gardner JD, Bysani C. Sakamuri SS, et al. Among authors: delafontaine p. Mol Cell Endocrinol. 2016 Jul 5;429:84-92. doi: 10.1016/j.mce.2016.03.038. Epub 2016 Apr 1. Mol Cell Endocrinol. 2016. PMID: 27040306 Free PMC article.
EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling.
Venkatesan B, Valente AJ, Prabhu SD, Shanmugam P, Delafontaine P, Chandrasekar B. Venkatesan B, et al. Among authors: delafontaine p. J Mol Cell Cardiol. 2010 Oct;49(4):655-63. doi: 10.1016/j.yjmcc.2010.05.007. Epub 2010 Jun 9. J Mol Cell Cardiol. 2010. PMID: 20538003 Free PMC article.
Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation.
Reddy VS, Prabhu SD, Mummidi S, Valente AJ, Venkatesan B, Shanmugam P, Delafontaine P, Chandrasekar B. Reddy VS, et al. Among authors: delafontaine p. Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1242-54. doi: 10.1152/ajpheart.00451.2010. Epub 2010 Aug 6. Am J Physiol Heart Circ Physiol. 2010. PMID: 20693392 Free PMC article.
β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo.
Murray DR, Mummidi S, Valente AJ, Yoshida T, Somanna NK, Delafontaine P, Dinarello CA, Chandrasekar B. Murray DR, et al. Among authors: delafontaine p. J Mol Cell Cardiol. 2012 Jan;52(1):206-18. doi: 10.1016/j.yjmcc.2011.09.022. Epub 2011 Oct 8. J Mol Cell Cardiol. 2012. PMID: 22004899 Free PMC article.
Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.
Valente AJ, Yoshida T, Murthy SN, Sakamuri SS, Katsuyama M, Clark RA, Delafontaine P, Chandrasekar B. Valente AJ, et al. Among authors: delafontaine p. Am J Physiol Heart Circ Physiol. 2012 Aug 1;303(3):H282-96. doi: 10.1152/ajpheart.00231.2012. Epub 2012 May 25. Am J Physiol Heart Circ Physiol. 2012. PMID: 22636674 Free PMC article.
198 results