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Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.
Messer AE, Bayliss CR, El-Mezgueldi M, Redwood CS, Ward DG, Leung MC, Papadaki M, Dos Remedios C, Marston SB. Messer AE, et al. Among authors: dos remedios c. Arch Biochem Biophys. 2016 Jul 1;601:113-20. doi: 10.1016/j.abb.2016.03.027. Epub 2016 Mar 29. Arch Biochem Biophys. 2016. PMID: 27036851 Free PMC article.
Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy.
Hoskins AC, Jacques A, Bardswell SC, McKenna WJ, Tsang V, dos Remedios CG, Ehler E, Adams K, Jalilzadeh S, Avkiran M, Watkins H, Redwood C, Marston SB, Kentish JC. Hoskins AC, et al. Among authors: dos remedios cg. J Mol Cell Cardiol. 2010 Nov;49(5):737-45. doi: 10.1016/j.yjmcc.2010.06.006. Epub 2010 Jul 6. J Mol Cell Cardiol. 2010. PMID: 20615414 Free PMC article.
GSK3β phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication.
Kuster DW, Sequeira V, Najafi A, Boontje NM, Wijnker PJ, Witjas-Paalberends ER, Marston SB, Dos Remedios CG, Carrier L, Demmers JA, Redwood C, Sadayappan S, van der Velden J. Kuster DW, et al. Among authors: dos remedios cg. Circ Res. 2013 Feb 15;112(4):633-9. doi: 10.1161/CIRCRESAHA.112.275602. Epub 2012 Dec 31. Circ Res. 2013. PMID: 23277198 Free PMC article.
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.
Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Arch Biochem Biophys. 2014 Jul 15;554:11-21. doi: 10.1016/j.abb.2014.04.017. Epub 2014 May 9. Arch Biochem Biophys. 2014. PMID: 24814372 Free PMC article.
OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency.
Marston S, Montgiraud C, Munster AB, Copeland O, Choi O, Dos Remedios C, Messer AE, Ehler E, Knöll R. Marston S, et al. Among authors: dos remedios c. PLoS One. 2015 Sep 25;10(9):e0138568. doi: 10.1371/journal.pone.0138568. eCollection 2015. PLoS One. 2015. PMID: 26406308 Free PMC article.
The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.
Dos Remedios CG, Lal SP, Li A, McNamara J, Keogh A, Macdonald PS, Cooke R, Ehler E, Knöll R, Marston SB, Stelzer J, Granzier H, Bezzina C, van Dijk S, De Man F, Stienen GJM, Odeberg J, Pontén F, Linke WA, Linke W, van der Velden J. Dos Remedios CG, et al. Biophys Rev. 2017 Aug;9(4):431-441. doi: 10.1007/s12551-017-0305-3. Epub 2017 Aug 14. Biophys Rev. 2017. PMID: 28808947 Free PMC article. Review.
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