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Page 1
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, Mbarek H, Li-Gao R, Trompet S, Verweij N, Evangelou E, Lyytikäinen LP, Tayo BO, Deelen J, van der Most PJ, van der Laan SW, Arking DE, Morrison A, Dehghan A, Franco OH, Hofman A, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Mychaleckyj JC, Campbell A, Hocking LJ, Padmanabhan S, Brody JA, Rice KM, White CC, Harris T, Isaacs A, Campbell H, Lange LA, Rudan I, Kolcic I, Navarro P, Zemunik T, Salomaa V; LifeLines Cohort Study; Kooner AS, Kooner JS, Lehne B, Scott WR, Tan ST, de Geus EJ, Milaneschi Y, Penninx BW, Willemsen G, de Mutsert R, Ford I, Gansevoort RT, Segura-Lepe MP, Raitakari OT, Viikari JS, Nikus K, Forrester T, McKenzie CA, de Craen AJ, de Ruijter HM; CHARGE Lipids Working Group; Pasterkamp G, Snieder H, Oldehinkel AJ, Slagboom PE, Cooper RS, Kähönen M, Lehtimäki T, Elliott P, van der Harst P, Jukema JW, Mook-Kanamori DO, Boomsma DI, Chambers JC, Swertz M, Ripatti S, Willems van Dijk K, Vitart V, Polasek O, Hayward C, Wilson JG, Wilson JF, Gudnason V, Rich SS, Psaty BM, Bor… See abstract for full author list ➔ van Leeuwen EM, et al. Among authors: van duijn cm, van der harst p, van klinken jb, van der laan sw, van der most pj. J Med Genet. 2016 Jul;53(7):441-9. doi: 10.1136/jmedgenet-2015-103439. Epub 2016 Apr 1. J Med Genet. 2016. PMID: 27036123 Free PMC article.
Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.
Kühnast S, Louwe MC, Heemskerk MM, Pieterman EJ, van Klinken JB, van den Berg SA, Smit JW, Havekes LM, Rensen PC, van der Hoorn JW, Princen HM, Jukema JW. Kühnast S, et al. Among authors: van klinken jb, van den berg sa, van der hoorn jw. PLoS One. 2013 Jun 19;8(6):e66467. doi: 10.1371/journal.pone.0066467. Print 2013. PLoS One. 2013. PMID: 23840481 Free PMC article.
Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study.
Bakker LE, Boon MR, van der Linden RA, Arias-Bouda LP, van Klinken JB, Smit F, Verberne HJ, Jukema JW, Tamsma JT, Havekes LM, van Marken Lichtenbelt WD, Jazet IM, Rensen PC. Bakker LE, et al. Among authors: van marken lichtenbelt wd, van klinken jb, van der linden ra. Lancet Diabetes Endocrinol. 2014 Mar;2(3):210-7. doi: 10.1016/S2213-8587(13)70156-6. Epub 2013 Nov 12. Lancet Diabetes Endocrinol. 2014. PMID: 24622751
Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.
Dharuri H, 't Hoen PA, van Klinken JB, Henneman P, Laros JF, Lips MA, El Bouazzaoui F, van Ommen GJ, Janssen I, van Ramshorst B, van Wagensveld BA, Pijl H, Willems van Dijk K, van Harmelen V. Dharuri H, et al. Among authors: van harmelen v, van wagensveld ba, van klinken jb, van ommen gj, van ramshorst b. Diabetologia. 2014 Nov;57(11):2384-92. doi: 10.1007/s00125-014-3347-0. Epub 2014 Aug 7. Diabetologia. 2014. PMID: 25099943
Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin.
Kühnast S, van der Tuin SJ, van der Hoorn JW, van Klinken JB, Simic B, Pieterman E, Havekes LM, Landmesser U, Lüscher TF, Willems van Dijk K, Rensen PC, Jukema JW, Princen HM. Kühnast S, et al. Among authors: van der tuin sj, van klinken jb, van der hoorn jw. Eur Heart J. 2015 Jan 1;36(1):39-48. doi: 10.1093/eurheartj/ehu319. Epub 2014 Aug 20. Eur Heart J. 2015. PMID: 25142968 Free PMC article.
Copy number variants in short children born small for gestational age.
Wit JM, van Duyvenvoorde HA, van Klinken JB, Caliebe J, Bosch CA, Lui JC, Gijsbers AC, Bakker E, Breuning MH, Oostdijk W, Losekoot M, Baron J, Binder G, Ranke MB, Ruivenkamp CA. Wit JM, et al. Among authors: van duyvenvoorde ha, van klinken jb. Horm Res Paediatr. 2014;82(5):310-8. doi: 10.1159/000367712. Epub 2014 Oct 8. Horm Res Paediatr. 2014. PMID: 25300501 Free PMC article. Clinical Trial.
The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice.
van Beek L, van Klinken JB, Pronk AC, van Dam AD, Dirven E, Rensen PC, Koning F, Willems van Dijk K, van Harmelen V. van Beek L, et al. Among authors: van harmelen v, van klinken jb, van dam ad. Diabetologia. 2015 Jul;58(7):1601-9. doi: 10.1007/s00125-015-3594-8. Epub 2015 May 12. Diabetologia. 2015. PMID: 25962520 Free PMC article.
Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study.
Liu J, Semiz S, van der Lee SJ, van der Spek A, Verhoeven A, van Klinken JB, Sijbrands E, Harms AC, Hankemeier T, van Dijk KW, van Duijn CM, Demirkan A. Liu J, et al. Among authors: van der spek a, van duijn cm, van der lee sj, van dijk kw, van klinken jb. Metabolomics. 2017;13(9):104. doi: 10.1007/s11306-017-1239-2. Epub 2017 Jul 28. Metabolomics. 2017. PMID: 28804275 Free PMC article.
CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.
Blauw LL, Li-Gao R, Noordam R, de Mutsert R, Trompet S, Berbée JFP, Wang Y, van Klinken JB, Christen T, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Rensen PCN, Willems van Dijk K. Blauw LL, et al. Among authors: van heemst d, van klinken jb. Circ Genom Precis Med. 2018 May;11(5):e002034. doi: 10.1161/CIRCGEN.117.002034. Circ Genom Precis Med. 2018. PMID: 29728394
64 results