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Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery.
Yang PY, Zou H, Chao E, Sherwood L, Nunez V, Keeney M, Ghartey-Tagoe E, Ding Z, Quirino H, Luo X, Welzel G, Chen G, Singh P, Woods AK, Schultz PG, Shen W. Yang PY, et al. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4140-5. doi: 10.1073/pnas.1601653113. Epub 2016 Mar 28. Proc Natl Acad Sci U S A. 2016. PMID: 27035989 Free PMC article.
Design of Potent and Proteolytically Stable Oxyntomodulin Analogs.
Muppidi A, Zou H, Yang PY, Chao E, Sherwood L, Nunez V, Woods AK, Schultz PG, Lin Q, Shen W. Muppidi A, et al. Among authors: yang py. ACS Chem Biol. 2016 Feb 19;11(2):324-8. doi: 10.1021/acschembio.5b00787. Epub 2016 Jan 4. ACS Chem Biol. 2016. PMID: 26727558 Free PMC article.
Recombinant thiopeptides containing noncanonical amino acids.
Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Luo X, et al. Among authors: yang py. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3615-20. doi: 10.1073/pnas.1602733113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976568 Free PMC article.
Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs.
Muppidi A, Lee SJ, Hsu CH, Zou H, Lee C, Pflimlin E, Mahankali M, Yang P, Chao E, Ahmad I, Crameri A, Wang D, Woods A, Shen W. Muppidi A, et al. Bioconjug Chem. 2019 Jan 16;30(1):83-89. doi: 10.1021/acs.bioconjchem.8b00764. Epub 2018 Dec 13. Bioconjug Chem. 2019. PMID: 30543420
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis.
Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, Mdluli KE, Franzblau S, Chatterjee AK, Johnsson K, Mikusova K, Besra GS, Fütterer K, Robbins SH, Barnes SW, Walker JR, Jacobs WR Jr, Schultz PG. Wang F, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7. doi: 10.1073/pnas.1309171110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776209 Free PMC article.
388 results