Dierssen M - Search Results

1

Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex.

Ruiz-Mejias M, Martinez de Lagran M, Mattia M, Castano-Prat P, Perez-Mendez L, Ciria-Suarez L, Gener T, Sancristobal B, García-Ojalvo J, Gruart A, Delgado-García JM, Sanchez-Vives MV, Dierssen M. Ruiz-Mejias M, et al. Among authors: dierssen m. J Neurosci. 2016 Mar 30;36(13):3648-59. doi: 10.1523/JNEUROSCI.2517-15.2016. J Neurosci. 2016. PMID: 27030752 Free PMC article.

2

Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction.

Martínez de Lagrán M, Altafaj X, Gallego X, Martí E, Estivill X, Sahún I, Fillat C, Dierssen M. Martínez de Lagrán M, et al. Among authors: dierssen m. Neurobiol Dis. 2004 Feb;15(1):132-42. doi: 10.1016/j.nbd.2003.10.002. Neurobiol Dis. 2004. PMID: 14751778

3

Haploinsufficiency of Dyrk1A in mice leads to specific alterations in the development and regulation of motor activity.

Fotaki V, Martínez De Lagrán M, Estivill X, Arbonés M, Dierssen M. Fotaki V, et al. Among authors: dierssen m. Behav Neurosci. 2004 Aug;118(4):815-21. doi: 10.1037/0735-7044.118.4.815. Behav Neurosci. 2004. PMID: 15301607

4

Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse.

Benavides-Piccione R, Dierssen M, Ballesteros-Yáñez I, Martínez de Lagrán M, Arbonés ML, Fotaki V, DeFelipe J, Elston GN. Benavides-Piccione R, et al. Among authors: dierssen m. Neurobiol Dis. 2005 Oct;20(1):115-22. doi: 10.1016/j.nbd.2005.02.004. Neurobiol Dis. 2005. PMID: 16137572

5

Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).

Martinez de Lagran M, Bortolozzi A, Millan O, Gispert JD, Gonzalez JR, Arbones ML, Artigas F, Dierssen M. Martinez de Lagran M, et al. Among authors: dierssen m. Genes Brain Behav. 2007 Aug;6(6):569-78. doi: 10.1111/j.1601-183X.2006.00285.x. Epub 2006 Nov 28. Genes Brain Behav. 2007. PMID: 17137466 Free article.

6

DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A): a gene with dosage effect during development and neurogenesis.

Dierssen M, de Lagrán MM. Dierssen M, et al. ScientificWorldJournal. 2006 Jun 17;6:1911-22. doi: 10.1100/tsw.2006.319. ScientificWorldJournal. 2006. PMID: 17205196 Free PMC article. Review.

7

Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway.

Vidal B, Serrano AL, Tjwa M, Suelves M, Ardite E, De Mori R, Baeza-Raja B, Martínez de Lagrán M, Lafuste P, Ruiz-Bonilla V, Jardí M, Gherardi R, Christov C, Dierssen M, Carmeliet P, Degen JL, Dewerchin M, Muñoz-Cánoves P. Vidal B, et al. Among authors: dierssen m. Genes Dev. 2008 Jul 1;22(13):1747-52. doi: 10.1101/gad.465908. Genes Dev. 2008. PMID: 18593877 Free PMC article.

8

Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.

Martinez de Lagran M, Benavides-Piccione R, Ballesteros-Yañez I, Calvo M, Morales M, Fillat C, Defelipe J, Ramakers GJ, Dierssen M. Martinez de Lagran M, et al. Among authors: dierssen m. Cereb Cortex. 2012 Dec;22(12):2867-77. doi: 10.1093/cercor/bhr362. Epub 2012 Jan 2. Cereb Cortex. 2012. PMID: 22215728

9

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome.

Altafaj X, Martín ED, Ortiz-Abalia J, Valderrama A, Lao-Peregrín C, Dierssen M, Fillat C. Altafaj X, et al. Among authors: dierssen m. Neurobiol Dis. 2013 Apr;52:117-27. doi: 10.1016/j.nbd.2012.11.017. Epub 2012 Dec 5. Neurobiol Dis. 2013. PMID: 23220201

10

Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular junction: possible role in Down syndrome.

Arque G, Casanovas A, Dierssen M. Arque G, et al. Among authors: dierssen m. PLoS One. 2013;8(1):e54285. doi: 10.1371/journal.pone.0054285. Epub 2013 Jan 16. PLoS One. 2013. PMID: 23342120 Free PMC article.

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