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Modeling the pharmacokinetic-pharmacodynamic relationship of the monoclonal anti-macaque-IL-15 antibody Hu714MuXHu in cynomolgus monkeys.
Pan WJ, Li H, Xiao JJ, Horner MJ, Lebrec HN, Butz EA, Kaliyaperumal A, Cheah TC, Ortiz RC, Prokop SP, Buntich SA, Boren BM, Wolford ST, Tsuji WH, Wienkers LC, Köck K. Pan WJ, et al. Among authors: prokop sp. Pharmacol Res Perspect. 2016 Jan 11;3(6):e00199. doi: 10.1002/prp2.199. eCollection 2015 Dec. Pharmacol Res Perspect. 2016. PMID: 27022472 Free PMC article.
Preclinical development of AMG 139, a human antibody specifically targeting IL-23.
Köck K, Pan WJ, Gow JM, Horner MJ, Gibbs JP, Colbert A, Goletz TJ, Newhall KJ, Rees WA, Sun Y, Zhang Y, O'Neill JC, Umble-Romero AN, Prokop SP, Krill CD, Som L, Buntich SA, Trimble MW, Tsuji WH, Towne JE. Köck K, et al. Among authors: prokop sp. Br J Pharmacol. 2015 Jan;172(1):159-72. doi: 10.1111/bph.12904. Epub 2014 Dec 15. Br J Pharmacol. 2015. PMID: 25205227 Free PMC article.
Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors.
Foti RS, Pearson JT, Wong SL, Zalikowski JA, Boudreaux MD, Prokop SP, Davis JA, Banfield C, Emery MG, Rock DA, Wahlstrom JL, Wienkers LC, Amore BM. Foti RS, et al. Among authors: prokop sp. Drug Metab Dispos. 2012 Dec;40(12):2239-49. doi: 10.1124/dmd.112.047928. Epub 2012 Aug 28. Drug Metab Dispos. 2012. PMID: 22930276