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Page 1
Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
Chattopadhyay D, Swingle MR, Salter EA, Wood E, D'Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, Banerjee S, Forbes D, Wierzbicki A, Honkanen RE. Chattopadhyay D, et al. Among authors: schroeder ce. Biochem Pharmacol. 2016 Jun 1;109:14-26. doi: 10.1016/j.bcp.2016.03.011. Epub 2016 Mar 23. Biochem Pharmacol. 2016. PMID: 27002182 Free PMC article.
A Pan-GTPase Inhibitor as a Molecular Probe.
Hong L, Guo Y, BasuRay S, Agola JO, Romero E, Simpson DS, Schroeder CE, Simons P, Waller A, Garcia M, Carter M, Ursu O, Gouveia K, Golden JE, Aubé J, Wandinger-Ness A, Sklar LA. Hong L, et al. Among authors: schroeder ce. PLoS One. 2015 Aug 6;10(8):e0134317. doi: 10.1371/journal.pone.0134317. eCollection 2015. PLoS One. 2015. PMID: 26247207 Free PMC article.
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.
Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, Golden JE, Aubé J, Hudson LG, Buranda T, Sklar LA, Wandinger-Ness A. Hong L, et al. Among authors: schroeder ce. J Biol Chem. 2013 Mar 22;288(12):8531-8543. doi: 10.1074/jbc.M112.435941. Epub 2013 Feb 4. J Biol Chem. 2013. PMID: 23382385 Free PMC article.
Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity.
Matharu DS, Flaherty DP, Simpson DS, Schroeder CE, Chung D, Yan D, Noah JW, Jonsson CB, White EL, Aubé J, Plemper RK, Severson WE, Golden JE. Matharu DS, et al. Among authors: schroeder ce. J Med Chem. 2014 Dec 26;57(24):10314-28. doi: 10.1021/jm500902x. Epub 2014 Dec 4. J Med Chem. 2014. PMID: 25399509 Free PMC article.
Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.
Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, Jonsson CB, Chung D, Golden JE. Schroeder CE, et al. J Med Chem. 2014 Oct 23;57(20):8608-21. doi: 10.1021/jm501203v. Epub 2014 Oct 7. J Med Chem. 2014. PMID: 25244572 Free PMC article.
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.
Chung DH, Golden JE, Adcock RS, Schroeder CE, Chu YK, Sotsky JB, Cramer DE, Chilton PM, Song C, Anantpadma M, Davey RA, Prodhan AI, Yin X, Zhang X. Chung DH, et al. Among authors: schroeder ce. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4552-62. doi: 10.1128/AAC.00282-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27185801 Free PMC article.
206 results