Honkanen RE - Search Results

1

Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.

Chattopadhyay D, Swingle MR, Salter EA, Wood E, D'Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, Banerjee S, Forbes D, Wierzbicki A, Honkanen RE. Chattopadhyay D, et al. Among authors: honkanen re. Biochem Pharmacol. 2016 Jun 1;109:14-26. doi: 10.1016/j.bcp.2016.03.011. Epub 2016 Mar 23. Biochem Pharmacol. 2016. PMID: 27002182 Free PMC article.

2

Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.

Honkanen RE. Honkanen RE. FEBS Lett. 1993 Sep 20;330(3):283-6. doi: 10.1016/0014-5793(93)80889-3. FEBS Lett. 1993. PMID: 8397101 Free article.

3

Photoreceptor serine/threonine protein phosphatase type 7: cloning, expression, and functional analysis.

Huang X, Swingle MR, Honkanen RE. Huang X, et al. Among authors: honkanen re. Methods Enzymol. 2000;315:579-93. doi: 10.1016/s0076-6879(00)15869-0. Methods Enzymol. 2000. PMID: 10736728 No abstract available.

4

Serine/threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling.

Dean DA, Urban G, Aragon IV, Swingle M, Miller B, Rusconi S, Bueno M, Dean NM, Honkanen RE. Dean DA, et al. Among authors: honkanen re. BMC Cell Biol. 2001;2:6. doi: 10.1186/1471-2121-2-6. Epub 2001 May 17. BMC Cell Biol. 2001. PMID: 11389770 Free PMC article.

5

Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition.

Buck SB, Hardouin C, Ichikawa S, Soenen DR, Gauss CM, Hwang I, Swingle MR, Bonness KM, Honkanen RE, Boger DL. Buck SB, et al. Among authors: honkanen re. J Am Chem Soc. 2003 Dec 24;125(51):15694-5. doi: 10.1021/ja038672n. J Am Chem Soc. 2003. PMID: 14677930

6

Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5.

Swingle MR, Honkanen RE, Ciszak EM. Swingle MR, et al. Among authors: honkanen re. J Biol Chem. 2004 Aug 6;279(32):33992-9. doi: 10.1074/jbc.M402855200. Epub 2004 May 23. J Biol Chem. 2004. PMID: 15155720 Free article.

7

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.

Lawhorn BG, Boga SB, Wolkenberg SE, Colby DA, Gauss CM, Swingle MR, Amable L, Honkanen RE, Boger DL. Lawhorn BG, et al. Among authors: honkanen re. J Am Chem Soc. 2006 Dec 27;128(51):16720-32. doi: 10.1021/ja066477d. J Am Chem Soc. 2006. PMID: 17177422 Free PMC article.

8

Small-molecule inhibitors of ser/thr protein phosphatases: specificity, use and common forms of abuse.

Swingle M, Ni L, Honkanen RE. Swingle M, et al. Among authors: honkanen re. Methods Mol Biol. 2007;365:23-38. doi: 10.1385/1-59745-267-X:23. Methods Mol Biol. 2007. PMID: 17200551 Free PMC article.

9

High yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors.

Ni L, Swingle MS, Bourgeois AC, Honkanen RE. Ni L, et al. Among authors: honkanen re. Assay Drug Dev Technol. 2007 Oct;5(5):645-53. doi: 10.1089/adt.2007.079. Assay Drug Dev Technol. 2007. PMID: 17939754 Free PMC article.

10

The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancer.

Golden T, Swingle M, Honkanen RE. Golden T, et al. Among authors: honkanen re. Cancer Metastasis Rev. 2008 Jun;27(2):169-78. doi: 10.1007/s10555-008-9125-z. Cancer Metastasis Rev. 2008. PMID: 18253812 Free PMC article. Review.

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