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mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).
de Joussineau C, Sahut-Barnola I, Tissier F, Dumontet T, Drelon C, Batisse-Lignier M, Tauveron I, Pointud JC, Lefrançois-Martinez AM, Stratakis CA, Bertherat J, Val P, Martinez A. de Joussineau C, et al. Among authors: stratakis ca. Hum Mol Genet. 2014 Oct 15;23(20):5418-28. doi: 10.1093/hmg/ddu265. Epub 2014 May 27. Hum Mol Genet. 2014. PMID: 24865460 Free PMC article.
Differentially regulated protein kinase A (PKA) activity in adipose tissue and liver is associated with resistance to diet-induced obesity and glucose intolerance in mice that lack PKA regulatory subunit type IIα.
London E, Nesterova M, Sinaii N, Szarek E, Chanturiya T, Mastroyannis SA, Gavrilova O, Stratakis CA. London E, et al. Among authors: stratakis ca. Endocrinology. 2014 Sep;155(9):3397-408. doi: 10.1210/en.2014-1122. Epub 2014 Jun 10. Endocrinology. 2014. PMID: 24914943 Free PMC article.
773 results