Tsai NP - Search Results

1

Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling.

Jewett KA, Christian CA, Bacos JT, Lee KY, Zhu J, Tsai NP. Jewett KA, et al. Among authors: tsai np. Mol Brain. 2016 Mar 22;9:32. doi: 10.1186/s13041-016-0214-6. Mol Brain. 2016. PMID: 27000207 Free PMC article.

2

The tumor suppressor p53 guides GluA1 homeostasis through Nedd4-2 during chronic elevation of neuronal activity.

Jewett KA, Zhu J, Tsai NP. Jewett KA, et al. Among authors: tsai np. J Neurochem. 2015 Oct;135(2):226-33. doi: 10.1111/jnc.13271. Epub 2015 Aug 27. J Neurochem. 2015. PMID: 26250624 Free article.

3

FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination.

Tsai NP, Wilkerson JR, Guo W, Huber KM. Tsai NP, et al. Hum Mol Genet. 2017 Jan 15;26(2):293-304. doi: 10.1093/hmg/ddw386. Hum Mol Genet. 2017. PMID: 28025327 Free PMC article.

4

Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.

Zhu J, Lee KY, Jewett KA, Man HY, Chung HJ, Tsai NP. Zhu J, et al. Among authors: tsai np. PLoS Genet. 2017 Feb 17;13(2):e1006634. doi: 10.1371/journal.pgen.1006634. eCollection 2017 Feb. PLoS Genet. 2017. PMID: 28212375 Free PMC article.

5

Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity.

Liu DC, Seimetz J, Lee KY, Kalsotra A, Chung HJ, Lu H, Tsai NP. Liu DC, et al. Among authors: tsai np. Hum Mol Genet. 2017 Oct 15;26(20):3895-3908. doi: 10.1093/hmg/ddx276. Hum Mol Genet. 2017. PMID: 29016848 Free PMC article.

6

Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2.

Lee KY, Jewett KA, Chung HJ, Tsai NP. Lee KY, et al. Among authors: tsai np. Hum Mol Genet. 2018 Aug 15;27(16):2805-2816. doi: 10.1093/hmg/ddy189. Hum Mol Genet. 2018. PMID: 29771335 Free PMC article.

7

Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice.

Jewett KA, Lee KY, Eagleman DE, Soriano S, Tsai NP. Jewett KA, et al. Among authors: tsai np. Neuropharmacology. 2018 Aug;138:182-192. doi: 10.1016/j.neuropharm.2018.06.011. Epub 2018 Jun 8. Neuropharmacology. 2018. PMID: 29890190 Free PMC article.

8

Reduced axonal surface expression and phosphoinositide sensitivity in K_v7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.

Kim EC, Zhang J, Pang W, Wang S, Lee KY, Cavaretta JP, Walters J, Procko E, Tsai NP, Chung HJ. Kim EC, et al. Among authors: tsai np. Neurobiol Dis. 2018 Oct;118:76-93. doi: 10.1016/j.nbd.2018.07.004. Epub 2018 Jul 6. Neurobiol Dis. 2018. PMID: 30008368 Free PMC article.

9

C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.

Zhu J, Lee KY, Jong TT, Tsai NP. Zhu J, et al. Among authors: tsai np. J Neurochem. 2019 Nov;151(3):289-300. doi: 10.1111/jnc.14840. Epub 2019 Aug 25. J Neurochem. 2019. PMID: 31357244 Free PMC article.

10

Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation.

Liu DC, Eagleman DE, Tsai NP. Liu DC, et al. Among authors: tsai np. PLoS Genet. 2019 Sep 26;15(9):e1008364. doi: 10.1371/journal.pgen.1008364. eCollection 2019 Sep. PLoS Genet. 2019. PMID: 31557161 Free PMC article.

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