Ortiz C - Search Results

1

Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi.

Ortiz C, Moraca F, Medeiros A, Botta M, Hamilton N, Comini MA. Ortiz C, et al. Molecules. 2016 Mar 17;21(3):368. doi: 10.3390/molecules21030368. Molecules. 2016. PMID: 26999093 Free PMC article.

2

Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate.

Ortíz C, Larrieux N, Medeiros A, Botti H, Comini M, Buschiazzo A. Ortíz C, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1457-61. doi: 10.1107/S1744309111037821. Epub 2011 Oct 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22102256 Free PMC article.

3

Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.

Ortíz C, Botti H, Buschiazzo A, Comini MA. Ortíz C, et al. J Mol Biol. 2019 May 17;431(11):2143-2162. doi: 10.1016/j.jmb.2019.03.023. Epub 2019 Mar 28. J Mol Biol. 2019. PMID: 30930048

4

Glucose 6-Phosphate Dehydrogenase from Trypanosomes: Selectivity for Steroids and Chemical Validation in Bloodstream Trypanosoma brucei.

Ortíz C, Moraca F, Laverriere M, Jordan A, Hamilton N, Comini MA. Ortíz C, et al. Molecules. 2021 Jan 12;26(2):358. doi: 10.3390/molecules26020358. Molecules. 2021. PMID: 33445584 Free PMC article.

5

Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.

Ballesteros-Casallas A, Quiroga C, Ortiz C, Benítez D, Denis PA, Figueroa D, Salas CO, Bertrand J, Tapia RA, Sánchez P, Miscione GP, Comini MA, Paulino M. Ballesteros-Casallas A, et al. Among authors: ortiz c. Eur J Med Chem. 2023 Jan 15;246:114926. doi: 10.1016/j.ejmech.2022.114926. Epub 2022 Nov 17. Eur J Med Chem. 2023. PMID: 36508970

6

Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction-Optimization Strategy Applied to Paullones.

Lindhof JC, Ihnatenko I, Müller MJ, Orban OCF, Ortíz C, Benítez D, Dibello E, Seidl LL, Comini MA, Kunick C. Lindhof JC, et al. Among authors: ortiz c. ChemMedChem. 2023 May 16;18(10):e202300036. doi: 10.1002/cmdc.202300036. Epub 2023 Mar 28. ChemMedChem. 2023. PMID: 36847711

7

The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones.

Ihnatenko I, Müller MJ, Orban OCF, Lindhof JC, Benítez D, Ortíz C, Dibello E, Seidl LL, Comini MA, Kunick C. Ihnatenko I, et al. Among authors: ortiz c. PLoS One. 2023 Nov 30;18(11):e0292946. doi: 10.1371/journal.pone.0292946. eCollection 2023. PLoS One. 2023. PMID: 38032881 Free PMC article.

8

The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

Manta B, Hugo M, Ortiz C, Ferrer-Sueta G, Trujillo M, Denicola A. Manta B, et al. Among authors: ortiz c. Arch Biochem Biophys. 2009 Apr 15;484(2):146-54. doi: 10.1016/j.abb.2008.11.017. Epub 2008 Nov 24. Arch Biochem Biophys. 2009. PMID: 19061854

9

[Successes and challenges in achieving and sustaining the elimination of measles, rubella, and congenital rubella syndrome in the Americas, 2013-2023Conquistas e desafios para alcançar e manter a eliminação do sarampo, da rubéola e da síndrome da rubéola congênita na Região das Américas, 2013-2023].

Pastor D, Bravo-Alcántara P, Durón R, Tirso CP, Ortiz C, Rey-Benito G. Pastor D, et al. Among authors: ortiz c. Rev Panam Salud Publica. 2024 Dec 18;48:e140. doi: 10.26633/RPSP.2024.140. eCollection 2024. Rev Panam Salud Publica. 2024. PMID: 39697269 Free PMC article. Spanish.

10

[Digital transformation in Honduras: an information system for surveillance of ESAVI/AESITransformação digital em Honduras: sistema de informações para a vigilância de ESAVI/EAIE].

Núñez SY, Ortiz C, Ávila A, Romualdo-Tello NM, Aguilar C. Núñez SY, et al. Among authors: ortiz c. Rev Panam Salud Publica. 2024 Dec 16;48:e127. doi: 10.26633/RPSP.2024.127. eCollection 2024. Rev Panam Salud Publica. 2024. PMID: 39687261 Free PMC article. Spanish.

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