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C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins.
Zhang YJ, Gendron TF, Grima JC, Sasaguri H, Jansen-West K, Xu YF, Katzman RB, Gass J, Murray ME, Shinohara M, Lin WL, Garrett A, Stankowski JN, Daughrity L, Tong J, Perkerson EA, Yue M, Chew J, Castanedes-Casey M, Kurti A, Wang ZS, Liesinger AM, Baker JD, Jiang J, Lagier-Tourenne C, Edbauer D, Cleveland DW, Rademakers R, Boylan KB, Bu G, Link CD, Dickey CA, Rothstein JD, Dickson DW, Fryer JD, Petrucelli L. Zhang YJ, et al. Among authors: rothstein jd. Nat Neurosci. 2016 May;19(5):668-677. doi: 10.1038/nn.4272. Epub 2016 Mar 21. Nat Neurosci. 2016. PMID: 26998601 Free PMC article.
Models of amyotrophic lateral sclerosis.
Jackson M, Ganel R, Rothstein JD. Jackson M, et al. Among authors: rothstein jd. Curr Protoc Neurosci. 2002 Nov;Chapter 9:Unit 9.13. doi: 10.1002/0471142301.ns0913s20. Curr Protoc Neurosci. 2002. PMID: 18428572 Review.
327 results