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MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency.
Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. Zhang H, et al. Among authors: liu l. Cell Stem Cell. 2016 Apr 7;18(4):481-94. doi: 10.1016/j.stem.2016.02.004. Epub 2016 Mar 17. Cell Stem Cell. 2016. PMID: 26996599 Free PMC article.
Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: liu l. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.
Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
Karatas H, Li Y, Liu L, Ji J, Lee S, Chen Y, Yang J, Huang L, Bernard D, Xu J, Townsend EC, Cao F, Ran X, Li X, Wen B, Sun D, Stuckey JA, Lei M, Dou Y, Wang S. Karatas H, et al. Among authors: liu l. J Med Chem. 2017 Jun 22;60(12):4818-4839. doi: 10.1021/acs.jmedchem.6b01796. Epub 2017 Jun 12. J Med Chem. 2017. PMID: 28603984
Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase.
Chern TR, Liu L, Petrunak E, Stuckey JA, Wang M, Bernard D, Zhou H, Lee S, Dou Y, Wang S. Chern TR, et al. Among authors: liu l. ACS Med Chem Lett. 2020 May 14;11(6):1348-1352. doi: 10.1021/acsmedchemlett.0c00229. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551023 Free PMC article.
73,562 results
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