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Different precore/core mutations of hepatitis B interact with, limit, or favor liver fibrosis severity.
Ducancelle A, Pivert A, Bertrais S, Boursier J, Balan V, Veillon P, le Guillou-Guillemette H, Thibault V, Castelain S, Roquebert B, Coste-Burel M, Mackiewicz V, Schvoerer E, Larrat S, Maylin S, Alain S, Loustaud-Ratti V, Gordien E, Gozlan J, Brodard V, Chevaliez S, Calès P, Lunel-Fabiani F. Ducancelle A, et al. J Gastroenterol Hepatol. 2016 Oct;31(10):1750-1756. doi: 10.1111/jgh.13338. J Gastroenterol Hepatol. 2016. PMID: 26992056
IL-34 and macrophage colony-stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells.
Preisser L, Miot C, Le Guillou-Guillemette H, Beaumont E, Foucher ED, Garo E, Blanchard S, Frémaux I, Croué A, Fouchard I, Lunel-Fabiani F, Boursier J, Roingeard P, Calès P, Delneste Y, Jeannin P. Preisser L, et al. Hepatology. 2014 Dec;60(6):1879-90. doi: 10.1002/hep.27328. Epub 2014 Oct 29. Hepatology. 2014. PMID: 25066464
Natural non-homologous recombination led to the emergence of a duplicated V3-NS5A region in HCV-1b strains associated with hepatocellular carcinoma.
Le Guillou-Guillemette H, Pivert A, Bouthry E, Henquell C, Petsaris O, Ducancelle A, Veillon P, Vallet S, Alain S, Thibault V, Abravanel F, Rosenberg AA, André-Garnier E, Bour JB, Baazia Y, Trimoulet P, André P, Gaudy-Graffin C, Bettinger D, Larrat S, Signori-Schmuck A, Saoudin H, Pozzetto B, Lagathu G, Minjolle-Cha S, Stoll-Keller F, Pawlotsky JM, Izopet J, Payan C, Lunel-Fabiani F, Lemaire C. Le Guillou-Guillemette H, et al. PLoS One. 2017 Apr 10;12(4):e0174651. doi: 10.1371/journal.pone.0174651. eCollection 2017. PLoS One. 2017. PMID: 28394908 Free PMC article.
HCV virology and diagnosis.
Roger S, Ducancelle A, Le Guillou-Guillemette H, Gaudy C, Lunel F. Roger S, et al. Clin Res Hepatol Gastroenterol. 2021 May;45(3):101626. doi: 10.1016/j.clinre.2021.101626. Epub 2021 Feb 23. Clin Res Hepatol Gastroenterol. 2021. PMID: 33636428 Review.
59 results