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Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice.
Koorneef LL, van den Heuvel JK, Kroon J, Boon MR, 't Hoen PAC, Hettne KM, van de Velde NM, Kolenbrander KB, Streefland TCM, Mol IM, Sips HCM, Kielbasa SM, Mei H, Belanoff JK, Pereira AM, Oosterveer MH, Hunt H, Rensen PCN, Meijer OC. Koorneef LL, et al. Among authors: van den heuvel jk. Endocrinology. 2018 Dec 1;159(12):3925-3936. doi: 10.1210/en.2018-00671. Endocrinology. 2018. PMID: 30321321
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S. Kroon J, et al. Among authors: van den heuvel jk. Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 3. Mol Metab. 2021. PMID: 33548499 Free PMC article.
Neuronal Control of Brown Fat Activity.
Kooijman S, van den Heuvel JK, Rensen PCN. Kooijman S, et al. Among authors: van den heuvel jk. Trends Endocrinol Metab. 2015 Nov;26(11):657-668. doi: 10.1016/j.tem.2015.09.008. Epub 2015 Oct 17. Trends Endocrinol Metab. 2015. PMID: 26482876 Review.
Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice.
Eggink HM, Tambyrajah LL, van den Berg R, Mol IM, van den Heuvel JK, Koehorst M, Groen AK, Boelen A, Kalsbeek A, Romijn JA, Rensen PCN, Kooijman S, Soeters MR. Eggink HM, et al. Among authors: van den heuvel jk. J Endocrinol. 2018 Feb;236(2):85-97. doi: 10.1530/JOE-17-0503. Epub 2017 Dec 12. J Endocrinol. 2018. PMID: 29233934
Genome-wide coexpression of steroid receptors in the mouse brain: Identifying signaling pathways and functionally coordinated regions.
Mahfouz A, Lelieveldt BP, Grefhorst A, van Weert LT, Mol IM, Sips HC, van den Heuvel JK, Datson NA, Visser JA, Reinders MJ, Meijer OC. Mahfouz A, et al. Among authors: van den heuvel jk. Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2738-43. doi: 10.1073/pnas.1520376113. Epub 2016 Jan 25. Proc Natl Acad Sci U S A. 2016. PMID: 26811448 Free PMC article.
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