Viswanadhan VN - Search Results

1

A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease.

Kalindjian SB, Kadnur SV, Hewson CA, Venkateshappa C, Juluri S, Kristam R, Kulkarni B, Mohammed Z, Saxena R, Viswanadhan VN, Aiyar J, McVey D. Kalindjian SB, et al. Among authors: viswanadhan vn. J Med Chem. 2016 Apr 14;59(7):3098-111. doi: 10.1021/acs.jmedchem.5b01840. Epub 2016 Mar 17. J Med Chem. 2016. PMID: 26987013

2

3D-QSAR analysis of TRPV1 inhibitors reveals a pharmacophore applicable to diverse scaffolds and clinical candidates.

Kristam R, Parmar V, Viswanadhan VN. Kristam R, et al. Among authors: viswanadhan vn. J Mol Graph Model. 2013 Sep;45:157-72. doi: 10.1016/j.jmgm.2013.08.014. Epub 2013 Aug 28. J Mol Graph Model. 2013. PMID: 24036505

3

TRPV1 antagonism by piperazinyl-aryl compounds: A Topomer-CoMFA study and its use in virtual screening for identification of novel antagonists.

Kristam R, Rao SN, D'Cruz AS, Mahadevan V, Viswanadhan VN. Kristam R, et al. Among authors: viswanadhan vn. J Mol Graph Model. 2017 Mar;72:112-128. doi: 10.1016/j.jmgm.2017.01.010. Epub 2017 Jan 7. J Mol Graph Model. 2017. PMID: 28092830

4

Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides.

Norman MH, Zhu J, Fotsch C, Bo Y, Chen N, Chakrabarti P, Doherty EM, Gavva NR, Nishimura N, Nixey T, Ognyanov VI, Rzasa RM, Stec M, Surapaneni S, Tamir R, Viswanadhan VN, Treanor JJ. Norman MH, et al. Among authors: viswanadhan vn. J Med Chem. 2007 Jul 26;50(15):3497-514. doi: 10.1021/jm070189q. Epub 2007 Jun 22. J Med Chem. 2007. PMID: 17585749

5

Toward a general predictive QSAR model for gamma-secretase inhibitors.

Ajmani S, Janardhan S, Viswanadhan VN. Ajmani S, et al. Among authors: viswanadhan vn. Mol Divers. 2013 Aug;17(3):421-34. doi: 10.1007/s11030-013-9441-2. Epub 2013 Apr 24. Mol Divers. 2013. PMID: 23612850

6

A neural network-based QSAR approach for exploration of diverse multi-tyrosine kinase inhibitors and its comparison with a fragment- based approach.

Ajmani S, Viswanadhan VN. Ajmani S, et al. Among authors: viswanadhan vn. Curr Comput Aided Drug Des. 2013 Dec;9(4):482-90. doi: 10.2174/15734099113096660046. Curr Comput Aided Drug Des. 2013. PMID: 24138419

7

Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents.

Bürli RW, Xu H, Zou X, Muller K, Golden J, Frohn M, Adlam M, Plant MH, Wong M, McElvain M, Regal K, Viswanadhan VN, Tagari P, Hungate R. Bürli RW, et al. Among authors: viswanadhan vn. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3713-8. doi: 10.1016/j.bmcl.2006.04.068. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16697190

8

Small molecule inhibitors of PIM1 kinase: July 2009 to February 2013 patent update.

Arunesh GM, Shanthi E, Krishna MH, Sooriya Kumar J, Viswanadhan VN. Arunesh GM, et al. Among authors: viswanadhan vn. Expert Opin Ther Pat. 2014 Jan;24(1):5-17. doi: 10.1517/13543776.2014.848196. Epub 2013 Oct 17. Expert Opin Ther Pat. 2014. PMID: 24131033 Review.

9

Three-dimensional quantitative structure-activity relationships and activity predictions of human TRPV1 channel antagonists: comparative molecular field analysis and comparative molecular similarity index analysis of cinnamides.

Viswanadhan VN, Sun Y, Norman MH. Viswanadhan VN, et al. J Med Chem. 2007 Nov 15;50(23):5608-19. doi: 10.1021/jm070261k. Epub 2007 Oct 19. J Med Chem. 2007. PMID: 17948977

10

Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity.

D'Amico DC, Aya T, Human J, Fotsch C, Chen JJ, Biswas K, Riahi B, Norman MH, Willoughby CA, Hungate R, Reider PJ, Biddlecome G, Lester-Zeiner D, Staden CV, Johnson E, Kamassah A, Arik L, Wang J, Viswanadhan VN, Groneberg RD, Zhan J, Suzuki H, Toro A, Mareska DA, Clarke DE, Harvey DM, Burgess LE, Laird ER, Askew B, Ng G. D'Amico DC, et al. Among authors: viswanadhan vn. J Med Chem. 2007 Feb 22;50(4):607-10. doi: 10.1021/jm061224g. Epub 2007 Jan 23. J Med Chem. 2007. PMID: 17243660

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