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Page 1
Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists.
Ammazzalorso A, Carrieri A, Verginelli F, Bruno I, Carbonara G, D'Angelo A, De Filippis B, Fantacuzzi M, Florio R, Fracchiolla G, Giampietro L, Giancristofaro A, Maccallini C, Cama A, Amoroso R. Ammazzalorso A, et al. Among authors: giancristofaro a. Eur J Med Chem. 2016 May 23;114:191-200. doi: 10.1016/j.ejmech.2016.02.064. Epub 2016 Feb 27. Eur J Med Chem. 2016. PMID: 26974385
Synthesis and biological evaluation of 2-heteroarylthioalkanoic acid analogues of clofibric acid as peroxisome proliferator-activated receptor alpha agonists.
Giampietro L, Ammazzalorso A, Giancristofaro A, Lannutti F, Bettoni G, De Filippis B, Fantacuzzi M, Maccallini C, Petruzzelli M, Morgano A, Moschetta A, Amoroso R. Giampietro L, et al. Among authors: giancristofaro a. J Med Chem. 2009 Oct 22;52(20):6224-32. doi: 10.1021/jm900878u. J Med Chem. 2009. PMID: 19791744
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs.
Giampietro L, D'Angelo A, Giancristofaro A, Ammazzalorso A, De Filippis B, Fantacuzzi M, Linciano P, Maccallini C, Amoroso R. Giampietro L, et al. Among authors: giancristofaro a. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7662-6. doi: 10.1016/j.bmcl.2012.09.111. Epub 2012 Oct 6. Bioorg Med Chem Lett. 2012. PMID: 23102891
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARα.
Ammazzalorso A, D'Angelo A, Giancristofaro A, De Filippis B, Di Matteo M, Fantacuzzi M, Giampietro L, Linciano P, Maccallini C, Amoroso R. Ammazzalorso A, et al. Among authors: giancristofaro a. Eur J Med Chem. 2012 Dec;58:317-22. doi: 10.1016/j.ejmech.2012.10.019. Epub 2012 Oct 23. Eur J Med Chem. 2012. PMID: 23137448