Hooper JD - Search Results

1

New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.

He Y, Harrington BS, Hooper JD. He Y, et al. Among authors: hooper jd. Oncoscience. 2016 Jan 29;3(1):5-8. doi: 10.18632/oncoscience.286. eCollection 2016. Oncoscience. 2016. PMID: 26973855 Free PMC article.

2

N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).

He Y, Ramsay AJ, Hunt ML, Whitbread AK, Myers SA, Hooper JD. He Y, et al. Among authors: hooper jd. Biochem J. 2008 May 15;412(1):45-55. doi: 10.1042/BJ20071722. Biochem J. 2008. PMID: 18260827

3

The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.

He Y, Hryciw DH, Carroll ML, Myers SA, Whitbread AK, Kumar S, Poronnik P, Hooper JD. He Y, et al. Among authors: hooper jd. J Biol Chem. 2008 Aug 29;283(35):24000-10. doi: 10.1074/jbc.M803361200. Epub 2008 Jun 24. J Biol Chem. 2008. PMID: 18577513 Free PMC article.

4

The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges.

Wortmann A, He Y, Deryugina EI, Quigley JP, Hooper JD. Wortmann A, et al. Among authors: hooper jd. IUBMB Life. 2009 Jul;61(7):723-30. doi: 10.1002/iub.198. IUBMB Life. 2009. PMID: 19514048 Free article. Review.

5

Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.

He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, Quigley JP, Leduc R, Kirchhofer D, Hooper JD. He Y, et al. Among authors: hooper jd. J Biol Chem. 2010 Aug 20;285(34):26162-73. doi: 10.1074/jbc.M109.096453. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551327 Free PMC article.

6

Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734.

Wortmann A, He Y, Christensen ME, Linn M, Lumley JW, Pollock PM, Waterhouse NJ, Hooper JD. Wortmann A, et al. Among authors: hooper jd. J Biol Chem. 2011 Dec 9;286(49):42303-42315. doi: 10.1074/jbc.M111.227462. Epub 2011 Oct 12. J Biol Chem. 2011. PMID: 21994943 Free PMC article.

7

The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.

Adams MN, Christensen ME, He Y, Waterhouse NJ, Hooper JD. Adams MN, et al. Among authors: hooper jd. PLoS One. 2011;6(11):e28018. doi: 10.1371/journal.pone.0028018. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140500 Free PMC article.

8

Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.

Casar B, He Y, Iconomou M, Hooper JD, Quigley JP, Deryugina EI. Casar B, et al. Among authors: hooper jd. Oncogene. 2012 Aug 30;31(35):3924-38. doi: 10.1038/onc.2011.555. Epub 2011 Dec 19. Oncogene. 2012. PMID: 22179830 Free PMC article.

9

The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration.

Dong Y, He Y, de Boer L, Stack MS, Lumley JW, Clements JA, Hooper JD. Dong Y, et al. Among authors: hooper jd. J Biol Chem. 2012 Mar 23;287(13):9792-9803. doi: 10.1074/jbc.M111.335448. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315226 Free PMC article.

10

EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.

Adams MN, Harrington BS, He Y, Davies CM, Wallace SJ, Chetty NP, Crandon AJ, Oliveira NB, Shannon CM, Coward JI, Lumley JW, Perrin LC, Armes JE, Hooper JD. Adams MN, et al. Among authors: hooper jd. Oncogene. 2015 Mar 12;34(11):1375-83. doi: 10.1038/onc.2014.88. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681947

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