Chan EC - Search Results

1

Multiple modes of inhibition of human cytochrome P450 2J2 by dronedarone, amiodarone and their active metabolites.

Karkhanis A, Lam HY, Venkatesan G, Koh SK, Chai CL, Zhou L, Hong Y, Kojodjojo P, Chan EC. Karkhanis A, et al. Among authors: chan ec. Biochem Pharmacol. 2016 May 1;107:67-80. doi: 10.1016/j.bcp.2016.03.005. Epub 2016 Mar 10. Biochem Pharmacol. 2016. PMID: 26972388

2

Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.

Teng WC, Oh JW, New LS, Wahlin MD, Nelson SD, Ho HK, Chan EC. Teng WC, et al. Among authors: chan ec. Mol Pharmacol. 2010 Oct;78(4):693-703. doi: 10.1124/mol.110.065839. Epub 2010 Jul 12. Mol Pharmacol. 2010. PMID: 20624855

3

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation.

Chan CY, New LS, Ho HK, Chan EC. Chan CY, et al. Among authors: chan ec. Toxicol Lett. 2011 Oct 30;206(3):314-24. doi: 10.1016/j.toxlet.2011.07.019. Epub 2011 Aug 5. Toxicol Lett. 2011. PMID: 21839818

4

Interaction of lapatinib with cytochrome P450 3A5.

Chan EC, New LS, Chua TB, Yap CW, Ho HK, Nelson SD. Chan EC, et al. Drug Metab Dispos. 2012 Jul;40(7):1414-22. doi: 10.1124/dmd.112.044958. Epub 2012 Apr 17. Drug Metab Dispos. 2012. PMID: 22511346

5

Urinary metabotyping of bladder cancer using two-dimensional gas chromatography time-of-flight mass spectrometry.

Pasikanti KK, Esuvaranathan K, Hong Y, Ho PC, Mahendran R, Raman Nee Mani L, Chiong E, Chan EC. Pasikanti KK, et al. Among authors: chan ec. J Proteome Res. 2013 Sep 6;12(9):3865-73. doi: 10.1021/pr4000448. Epub 2013 Aug 7. J Proteome Res. 2013. PMID: 23885889

6

Metabotyping of docosahexaenoic acid - treated Alzheimer's disease cell model.

Bahety P, Tan YM, Hong Y, Zhang L, Chan EC, Ee PL. Bahety P, et al. Among authors: chan ec. PLoS One. 2014 Feb 27;9(2):e90123. doi: 10.1371/journal.pone.0090123. eCollection 2014. PLoS One. 2014. PMID: 24587236 Free PMC article.

7

Metabonomic profiling of bladder cancer.

Chan EC, Pasikanti KK, Hong Y, Ho PC, Mahendran R, Raman Nee Mani L, Chiong E, Esuvaranathan K. Chan EC, et al. J Proteome Res. 2015 Feb 6;14(2):587-602. doi: 10.1021/pr500966h. Epub 2014 Nov 26. J Proteome Res. 2015. PMID: 25388527 Review.

8

In vitro pharmacodynamics of various antibiotics in combination against extensively drug-resistant Klebsiella pneumoniae.

Lim TP, Cai Y, Hong Y, Chan EC, Suranthran S, Teo JQ, Lee WH, Tan TY, Hsu LY, Koh TH, Tan TT, Kwa AL. Lim TP, et al. Among authors: chan ec. Antimicrob Agents Chemother. 2015 May;59(5):2515-24. doi: 10.1128/AAC.03639-14. Epub 2015 Feb 17. Antimicrob Agents Chemother. 2015. PMID: 25691628 Free PMC article.

9

Meclizine, a pregnane X receptor agonist, is a direct inhibitor and mechanism-based inactivator of human cytochrome P450 3A.

Foo WY, Tay HY, Chan EC, Lau AJ. Foo WY, et al. Among authors: chan ec. Biochem Pharmacol. 2015 Oct 1;97(3):320-30. doi: 10.1016/j.bcp.2015.07.036. Epub 2015 Jul 31. Biochem Pharmacol. 2015. PMID: 26239802

10

Global Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress.

Chen L, Li J, Guo T, Ghosh S, Koh SK, Tian D, Zhang L, Jia D, Beuerman RW, Aebersold R, Chan EC, Zhou L. Chen L, et al. Among authors: chan ec. J Proteome Res. 2015 Sep 4;14(9):3982-95. doi: 10.1021/acs.jproteome.5b00443. Epub 2015 Aug 19. J Proteome Res. 2015. PMID: 26260330

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