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Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor.
Jozwiak K, Targowska-Duda KM, Kaczor AA, Kozak J, Ligeza A, Szacon E, Wrobel TM, Budzynska B, Biala G, Fornal E, Poso A, Wainer IW, Matosiuk D. Jozwiak K, et al. Bioorg Med Chem. 2014 Dec 15;22(24):6846-56. doi: 10.1016/j.bmc.2014.10.036. Epub 2014 Oct 31. Bioorg Med Chem. 2014. PMID: 25464883
Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes.
Arias HR, Feuerbach D, Targowska-Duda K, Kaczor AA, Poso A, Jozwiak K. Arias HR, et al. Biochim Biophys Acta. 2015 Feb;1848(2):731-41. doi: 10.1016/j.bbamem.2014.11.003. Epub 2014 Dec 2. Biochim Biophys Acta. 2015. PMID: 25475645 Free article.
Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.
Arias HR, Ravazzini F, Targowska-Duda KM, Kaczor AA, Feuerbach D, Boffi JC, Draczkowski P, Montag D, Brown BM, Elgoyhen AB, Jozwiak K, Puia G. Arias HR, et al. Int J Biochem Cell Biol. 2016 Jul;76:19-30. doi: 10.1016/j.biocel.2016.04.015. Epub 2016 Apr 26. Int J Biochem Cell Biol. 2016. PMID: 27129924
Corrigendum to "In vitro, molecular modeling and behavioral studies of '3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic" [Neurochem. Int. 96 (2016) 84-99].
Kaczor AA, Targowska-Duda KM, Budzyńska B, Biała G, Silva AG, Castro M. Kaczor AA, et al. Neurochem Int. 2016 Nov;100:178-180. doi: 10.1016/j.neuint.2016.10.010. Neurochem Int. 2016. PMID: 27825475 No abstract available.
49 results