Kirkland JL - Search Results

1

Translating the Science of Aging into Therapeutic Interventions.

Kirkland JL. Kirkland JL. Cold Spring Harb Perspect Med. 2016 Mar 1;6(3):a025908. doi: 10.1101/cshperspect.a025908. Cold Spring Harb Perspect Med. 2016. PMID: 26931808 Free PMC article. Review.

2

Healthspan, translation, and new outcomes for animal studies of aging.

Kirkland JL, Peterson C. Kirkland JL, et al. J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):209-12. doi: 10.1093/gerona/gln063. Epub 2009 Feb 5. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19196900 Free PMC article. Review.

3

Translating advances from the basic biology of aging into clinical application.

Kirkland JL. Kirkland JL. Exp Gerontol. 2013 Jan;48(1):1-5. doi: 10.1016/j.exger.2012.11.014. Epub 2012 Dec 10. Exp Gerontol. 2013. PMID: 23237984 Free PMC article. Review.

4

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.

Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Tchkonia T, et al. Among authors: kirkland jl. J Clin Invest. 2013 Mar;123(3):966-72. doi: 10.1172/JCI64098. Epub 2013 Mar 1. J Clin Invest. 2013. PMID: 23454759 Free PMC article. Review.

5

Resilience in Aging Mice.

Kirkland JL, Stout MB, Sierra F. Kirkland JL, et al. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1407-1414. doi: 10.1093/gerona/glw086. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535963 Free PMC article.

6

Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.

Burd CE, Gill MS, Niedernhofer LJ, Robbins PD, Austad SN, Barzilai N, Kirkland JL. Burd CE, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1388-1394. doi: 10.1093/gerona/glw112. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535964 Free PMC article.

7

Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes.

Justice J, Miller JD, Newman JC, Hashmi SK, Halter J, Austad SN, Barzilai N, Kirkland JL. Justice J, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1415-1423. doi: 10.1093/gerona/glw126. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535966 Free PMC article.

8

Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience.

Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN. Huffman DM, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1395-1406. doi: 10.1093/gerona/glw106. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535967 Free PMC article.

9

Strategies and Challenges in Clinical Trials Targeting Human Aging.

Newman JC, Milman S, Hashmi SK, Austad SN, Kirkland JL, Halter JB, Barzilai N. Newman JC, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1424-1434. doi: 10.1093/gerona/glw149. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535968 Free PMC article.

10

Molecular pathology endpoints useful for aging studies.

Niedernhofer LJ, Kirkland JL, Ladiges W. Niedernhofer LJ, et al. Among authors: kirkland jl. Ageing Res Rev. 2017 May;35:241-249. doi: 10.1016/j.arr.2016.09.012. Epub 2016 Oct 6. Ageing Res Rev. 2017. PMID: 27721062 Free PMC article. Review.

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