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Biophysical principles predict fitness landscapes of drug resistance.
Rodrigues JV, Bershtein S, Li A, Lozovsky ER, Hartl DL, Shakhnovich EI. Rodrigues JV, et al. Among authors: lozovsky er. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1470-8. doi: 10.1073/pnas.1601441113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929328 Free PMC article.
Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Lozovsky ER, et al. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12025-30. doi: 10.1073/pnas.0905922106. Epub 2009 Jul 8. Proc Natl Acad Sci U S A. 2009. PMID: 19587242 Free PMC article.
Relevance of Higher-Order Epistasis in Drug Resistance.
Lozovsky ER, Daniels RF, Heffernan GD, Jacobus DP, Hartl DL. Lozovsky ER, et al. Mol Biol Evol. 2021 Jan 4;38(1):142-151. doi: 10.1093/molbev/msaa196. Mol Biol Evol. 2021. PMID: 32745183 Free PMC article.
13 results