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Biophysical principles predict fitness landscapes of drug resistance.
Rodrigues JV, Bershtein S, Li A, Lozovsky ER, Hartl DL, Shakhnovich EI. Rodrigues JV, et al. Among authors: hartl dl. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1470-8. doi: 10.1073/pnas.1601441113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929328 Free PMC article.
Unexpected stability of mariner transgenes in Drosophila.
Lozovsky ER, Nurminsky D, Wimmer EA, Hartl DL. Lozovsky ER, et al. Among authors: hartl dl. Genetics. 2002 Feb;160(2):527-35. doi: 10.1093/genetics/160.2.527. Genetics. 2002. PMID: 11861559 Free PMC article.
Accelerated evolution of resistance in multidrug environments.
Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Hegreness M, et al. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13977-81. doi: 10.1073/pnas.0805965105. Epub 2008 Sep 8. Proc Natl Acad Sci U S A. 2008. PMID: 18779569 Free PMC article.
Optimization of gene expression by natural selection.
Bedford T, Hartl DL. Bedford T, et al. Among authors: hartl dl. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1133-8. doi: 10.1073/pnas.0812009106. Epub 2009 Jan 12. Proc Natl Acad Sci U S A. 2009. PMID: 19139403 Free PMC article.
Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Lozovsky ER, et al. Among authors: hartl dl. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12025-30. doi: 10.1073/pnas.0905922106. Epub 2009 Jul 8. Proc Natl Acad Sci U S A. 2009. PMID: 19587242 Free PMC article.
406 results