Rawls K - Search Results

1

Identifying metabolic adaptations characteristic of cardiotoxicity using paired transcriptomics and metabolomics data integrated with a computational model of heart metabolism.

Dougherty BV, Moore CJ, Rawls KD, Jenior ML, Chun B, Nagdas S, Saucerman JJ, Kolling GL, Wallqvist A, Papin JA. Dougherty BV, et al. Among authors: rawls kd. PLoS Comput Biol. 2024 Feb 29;20(2):e1011919. doi: 10.1371/journal.pcbi.1011919. eCollection 2024 Feb. PLoS Comput Biol. 2024. PMID: 38422168 Free PMC article.

2

Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response.

Roller DG, Hoang SA, Rawls KD, Owen KA, Simmers MB, Figler RA, Wulfkuhle JD, Petricoin EF, Wamhoff BR, Gioeli D. Roller DG, et al. Among authors: rawls kd. Sci Rep. 2021 Mar 10;11(1):5535. doi: 10.1038/s41598-021-84612-z. Sci Rep. 2021. PMID: 33692370 Free PMC article.

3

Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model.

Dougherty BV, Rawls KD, Kolling GL, Vinnakota KC, Wallqvist A, Papin JA. Dougherty BV, et al. Among authors: rawls kd. Cell Rep. 2021 Mar 9;34(10):108836. doi: 10.1016/j.celrep.2021.108836. Cell Rep. 2021. PMID: 33691118 Free article.

4

Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model.

Rawls KD, Dougherty BV, Vinnakota KC, Pannala VR, Wallqvist A, Kolling GL, Papin JA. Rawls KD, et al. Toxicol Appl Pharmacol. 2021 Feb 1;412:115390. doi: 10.1016/j.taap.2020.115390. Epub 2020 Dec 31. Toxicol Appl Pharmacol. 2021. PMID: 33387578 Free PMC article.

5

Metabolic Network Reconstructions to Predict Drug Targets and Off-Target Effects.

Rawls K, Dougherty BV, Papin J. Rawls K, et al. Methods Mol Biol. 2020;2088:315-330. doi: 10.1007/978-1-0716-0159-4_14. Methods Mol Biol. 2020. PMID: 31893380 Review.

6

Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary Hepatocytes.

Rawls KD, Blais EM, Dougherty BV, Vinnakota KC, Pannala VR, Wallqvist A, Kolling GL, Papin JA. Rawls KD, et al. Toxicol Sci. 2019 Dec 1;172(2):279-291. doi: 10.1093/toxsci/kfz197. Toxicol Sci. 2019. PMID: 31501904 Free PMC article.

7

Mechanistic identification of biofluid metabolite changes as markers of acetaminophen-induced liver toxicity in rats.

Pannala VR, Vinnakota KC, Rawls KD, Estes SK, O'Brien TP, Printz RL, Papin JA, Reifman J, Shiota M, Young JD, Wallqvist A. Pannala VR, et al. Among authors: rawls kd. Toxicol Appl Pharmacol. 2019 Jun 1;372:19-32. doi: 10.1016/j.taap.2019.04.001. Epub 2019 Apr 8. Toxicol Appl Pharmacol. 2019. PMID: 30974156 Free PMC article.

8

A simplified metabolic network reconstruction to promote understanding and development of flux balance analysis tools.

Rawls KD, Dougherty BV, Blais EM, Stancliffe E, Kolling GL, Vinnakota K, Pannala VR, Wallqvist A, Papin JA. Rawls KD, et al. Comput Biol Med. 2019 Feb;105:64-71. doi: 10.1016/j.compbiomed.2018.12.010. Epub 2018 Dec 17. Comput Biol Med. 2019. PMID: 30584952 Free article.

9

Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions.

Blais EM, Rawls KD, Dougherty BV, Li ZI, Kolling GL, Ye P, Wallqvist A, Papin JA. Blais EM, et al. Among authors: rawls kd. Nat Commun. 2017 Feb 8;8:14250. doi: 10.1038/ncomms14250. Nat Commun. 2017. PMID: 28176778 Free PMC article.

10

Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival.

den Hollander P, Rawls K, Tsimelzon A, Shepherd J, Mazumdar A, Hill J, Fuqua SA, Chang JC, Osborne CK, Hilsenbeck SG, Mills GB, Brown PH. den Hollander P, et al. Among authors: rawls k. Cancer Res. 2016 Apr 1;76(7):1942-53. doi: 10.1158/0008-5472.CAN-14-0673. Epub 2016 Feb 26. Cancer Res. 2016. PMID: 26921331 Free PMC article.

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