Rao L - Search Results

1

Synthesis of 3-acyloxyxanthone derivatives as α-glucosidase inhibitors: A further insight into the 3-substituents' effect.

Li GL, Cai CY, He JY, Rao L, Ma L, Liu Y, Wang B. Li GL, et al. Among authors: rao l. Bioorg Med Chem. 2016 Apr 1;24(7):1431-8. doi: 10.1016/j.bmc.2016.01.022. Epub 2016 Jan 21. Bioorg Med Chem. 2016. PMID: 26917220

2

Synthesis and biological evaluation of novel inhibitors against 1,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea.

Chen H, Han X, Qin N, Wei L, Yang Y, Rao L, Chi B, Feng L, Ren Y, Wan J. Chen H, et al. Among authors: rao l. Bioorg Med Chem. 2016 Mar 15;24(6):1225-30. doi: 10.1016/j.bmc.2016.01.053. Epub 2016 Jan 29. Bioorg Med Chem. 2016. PMID: 26860927

3

Analogues of xanthones--Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates.

Cai CY, Rao L, Rao Y, Guo JX, Xiao ZZ, Cao JY, Huang ZS, Wang B. Cai CY, et al. Among authors: rao l, rao y. Eur J Med Chem. 2017 Apr 21;130:51-59. doi: 10.1016/j.ejmech.2017.02.007. Epub 2017 Feb 7. Eur J Med Chem. 2017. PMID: 28242551

4

Design, synthesis and algicides activities of thiourea derivatives as the novel scaffold aldolase inhibitors.

Xiao S, Wei L, Hong Z, Rao L, Ren Y, Wan J, Feng L. Xiao S, et al. Among authors: rao l. Bioorg Med Chem. 2019 Mar 1;27(5):805-812. doi: 10.1016/j.bmc.2019.01.023. Epub 2019 Jan 24. Bioorg Med Chem. 2019. PMID: 30711311

5

Discovery of novel allosteric site and covalent inhibitors of FBPase with potent hypoglycemic effects.

Huang Y, Wei L, Han X, Chen H, Ren Y, Xu Y, Song R, Rao L, Su C, Peng C, Feng L, Wan J. Huang Y, et al. Among authors: rao l. Eur J Med Chem. 2019 Dec 15;184:111749. doi: 10.1016/j.ejmech.2019.111749. Epub 2019 Sep 30. Eur J Med Chem. 2019. PMID: 31589992

6

Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction.

Huang Y, Xu Y, Song R, Ni S, Liu J, Xu Y, Ren Y, Rao L, Wang Y, Wei L, Feng L, Su C, Peng C, Li J, Wan J. Huang Y, et al. Among authors: rao l. J Med Chem. 2020 Jun 11;63(11):6238-6247. doi: 10.1021/acs.jmedchem.0c00699. Epub 2020 May 19. J Med Chem. 2020. PMID: 32375478

7

Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis.

Wen W, Cao H, Huang Y, Tu J, Wan C, Wan J, Han X, Chen H, Liu J, Rao L, Su C, Peng C, Sheng C, Ren Y. Wen W, et al. Among authors: rao l. J Med Chem. 2022 Feb 10;65(3):2656-2674. doi: 10.1021/acs.jmedchem.1c02102. Epub 2022 Jan 31. J Med Chem. 2022. PMID: 35099959

8

N-Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction.

Wen W, Cao H, Xu Y, Ren Y, Rao L, Shao X, Chen H, Wu L, Liu J, Su C, Peng C, Huang Y, Wan J. Wen W, et al. Among authors: rao l. J Med Chem. 2022 Jul 14;65(13):9126-9143. doi: 10.1021/acs.jmedchem.2c00336. Epub 2022 Jul 4. J Med Chem. 2022. PMID: 35786925

9

In silico screening of a novel scaffold for fructose-1,6-bisphosatase (FBPase) inhibitors.

Huang Y, Chi B, Xu Y, Song R, Wei L, Rao L, Feng L, Ren Y, Wan J. Huang Y, et al. Among authors: rao l. J Mol Graph Model. 2019 Jan;86:142-148. doi: 10.1016/j.jmgm.2018.10.017. Epub 2018 Oct 20. J Mol Graph Model. 2019. PMID: 30366190

10

Structure-Guided Design of Affinity/Covalent-Bond Dual-Driven Inhibitors Targeting the AMP Site of FBPase.

Cao H, Huang Z, Liu Z, Zhang X, Ren Y, Hameed MS, Rao L, Makunga NP, Dobrikov GM, Wan J. Cao H, et al. Among authors: rao l. J Med Chem. 2024 Nov 28;67(22):20421-20437. doi: 10.1021/acs.jmedchem.4c01886. Epub 2024 Nov 9. J Med Chem. 2024. PMID: 39520680

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