Ghosh P - Search Results

1

Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer.

Barbazan J, Dunkel Y, Li H, Nitsche U, Janssen KP, Messer K, Ghosh P. Barbazan J, et al. Among authors: ghosh p. Sci Rep. 2016 Feb 26;6:22112. doi: 10.1038/srep22112. Sci Rep. 2016. PMID: 26916336 Free PMC article.

2

A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.

Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG. Garcia-Marcos M, et al. Among authors: ghosh p. J Biol Chem. 2010 Apr 23;285(17):12765-77. doi: 10.1074/jbc.M109.045161. Epub 2010 Feb 15. J Biol Chem. 2010. PMID: 20157114 Free PMC article.

3

Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer.

Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P. Garcia-Marcos M, et al. Among authors: ghosh p. FASEB J. 2011 Feb;25(2):590-9. doi: 10.1096/fj.10-167304. Epub 2010 Oct 25. FASEB J. 2011. PMID: 20974669 Free PMC article.

4

GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression.

Ghosh P, Garcia-Marcos M, Farquhar MG. Ghosh P, et al. Cell Adh Migr. 2011 May-Jun;5(3):237-48. doi: 10.4161/cam.5.3.15909. Epub 2011 May 1. Cell Adh Migr. 2011. PMID: 21546796 Free PMC article.

5

G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.

Garcia-Marcos M, Kietrsunthorn PS, Wang H, Ghosh P, Farquhar MG. Garcia-Marcos M, et al. Among authors: ghosh p. J Biol Chem. 2011 Aug 12;286(32):28138-49. doi: 10.1074/jbc.M110.204099. Epub 2011 Jun 8. J Biol Chem. 2011. PMID: 21653697 Free PMC article.

6

Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling.

Garcia-Marcos M, Kietrsunthorn PS, Pavlova Y, Adia MA, Ghosh P, Farquhar MG. Garcia-Marcos M, et al. Among authors: ghosh p. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1961-6. doi: 10.1073/pnas.1120538109. Epub 2012 Jan 25. Proc Natl Acad Sci U S A. 2012. PMID: 22308453 Free PMC article.

7

STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis.

Dunkel Y, Ong A, Notani D, Mittal Y, Lam M, Mi X, Ghosh P. Dunkel Y, et al. Among authors: ghosh p. J Biol Chem. 2012 Dec 7;287(50):41667-83. doi: 10.1074/jbc.M112.390781. Epub 2012 Oct 12. J Biol Chem. 2012. PMID: 23066027 Free PMC article.

8

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin.

López-Sánchez I, Garcia-Marcos M, Mittal Y, Aznar N, Farquhar MG, Ghosh P. López-Sánchez I, et al. Among authors: ghosh p. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5510-5. doi: 10.1073/pnas.1303392110. Epub 2013 Mar 18. Proc Natl Acad Sci U S A. 2013. PMID: 23509302 Free PMC article.

9

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P. Lopez-Sanchez I, et al. Among authors: ghosh p. Nat Commun. 2014 Jul 21;5:4451. doi: 10.1038/ncomms5451. Nat Commun. 2014. PMID: 25043713 Free PMC article.

10

Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.

Midde KK, Aznar N, Laederich MB, Ma GS, Kunkel MT, Newton AC, Ghosh P. Midde KK, et al. Among authors: ghosh p. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E937-46. doi: 10.1073/pnas.1420140112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25713130 Free PMC article.

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