Dahl A - Search Results

1

A multiple-phenotype imputation method for genetic studies.

Dahl A, Iotchkova V, Baud A, Johansson Å, Gyllensten U, Soranzo N, Mott R, Kranis A, Marchini J. Dahl A, et al. Nat Genet. 2016 Apr;48(4):466-72. doi: 10.1038/ng.3513. Epub 2016 Feb 22. Nat Genet. 2016. PMID: 26901065 Free PMC article.

2

Reverse GWAS: Using genetics to identify and model phenotypic subtypes.

Dahl A, Cai N, Ko A, Laakso M, Pajukanta P, Flint J, Zaitlen N. Dahl A, et al. PLoS Genet. 2019 Apr 5;15(4):e1008009. doi: 10.1371/journal.pgen.1008009. eCollection 2019 Apr. PLoS Genet. 2019. PMID: 30951530 Free PMC article.

3

Ultrarare variants drive substantial cis heritability of human gene expression.

Hernandez RD, Uricchio LH, Hartman K, Ye C, Dahl A, Zaitlen N. Hernandez RD, et al. Among authors: dahl a. Nat Genet. 2019 Sep;51(9):1349-1355. doi: 10.1038/s41588-019-0487-7. Epub 2019 Sep 2. Nat Genet. 2019. PMID: 31477931 Free PMC article.

4

A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits.

Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N. Dahl A, et al. Am J Hum Genet. 2020 Jan 2;106(1):71-91. doi: 10.1016/j.ajhg.2019.11.015. Am J Hum Genet. 2020. PMID: 31901249 Free PMC article.

5

Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder.

Dahl A, Thompson M, An U, Krebs M, Appadurai V, Border R, Bacanu SA, Werge T, Flint J, Schork AJ, Sankararaman S, Kendler KS, Cai N. Dahl A, et al. Nat Genet. 2023 Dec;55(12):2082-2093. doi: 10.1038/s41588-023-01559-9. Epub 2023 Nov 20. Nat Genet. 2023. PMID: 37985818 Free PMC article.

6

Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries.

An U, Pazokitoroudi A, Alvarez M, Huang L, Bacanu S, Schork AJ, Kendler K, Pajukanta P, Flint J, Zaitlen N, Cai N, Dahl A, Sankararaman S. An U, et al. Among authors: dahl a. Nat Genet. 2023 Dec;55(12):2269-2276. doi: 10.1038/s41588-023-01558-w. Epub 2023 Nov 20. Nat Genet. 2023. PMID: 37985819 Free PMC article.

7

Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression.

Peterson RE, Cai N, Dahl AW, Bigdeli TB, Edwards AC, Webb BT, Bacanu SA, Zaitlen N, Flint J, Kendler KS. Peterson RE, et al. Am J Psychiatry. 2018 Jun 1;175(6):545-554. doi: 10.1176/appi.ajp.2017.17060621. Epub 2018 Mar 2. Am J Psychiatry. 2018. PMID: 29495898 Free PMC article.

8

Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives.

Dahl A, Guillemot V, Mefford J, Aschard H, Zaitlen N. Dahl A, et al. Genetics. 2019 Apr;211(4):1179-1189. doi: 10.1534/genetics.118.301768. Epub 2019 Jan 28. Genetics. 2019. PMID: 30692194 Free PMC article.

9

On Negative Heritability and Negative Estimates of Heritability.

Steinsaltz D, Dahl A, Wachter KW. Steinsaltz D, et al. Among authors: dahl a. Genetics. 2020 Jun;215(2):343-357. doi: 10.1534/genetics.120.303161. Epub 2020 Apr 14. Genetics. 2020. PMID: 32291292 Free PMC article.

10

Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex traits.

Tang D, Freudenberg J, Dahl A. Tang D, et al. Among authors: dahl a. Am J Hum Genet. 2023 Nov 2;110(11):1875-1887. doi: 10.1016/j.ajhg.2023.10.002. Am J Hum Genet. 2023. PMID: 37922884 Free PMC article.

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