Muthas D - Search Results

1

The value of integrating pre-clinical data to predict nausea and vomiting risk in humans as illustrated by AZD3514, a novel androgen receptor modulator.

Grant C, Ewart L, Muthas D, Deavall D, Smith SA, Clack G, Newham P. Grant C, et al. Among authors: muthas d. Toxicol Appl Pharmacol. 2016 Apr 1;296:10-8. doi: 10.1016/j.taap.2016.02.007. Epub 2016 Feb 11. Toxicol Appl Pharmacol. 2016. PMID: 26876616 Clinical Trial.

2

Application of data mining and visualization techniques for the prediction of drug-induced nausea in man.

Parkinson J, Muthas D, Clark M, Boyer S, Valentin JP, Ewart L. Parkinson J, et al. Among authors: muthas d. Toxicol Sci. 2012 Mar;126(1):275-84. doi: 10.1093/toxsci/kfr334. Epub 2011 Dec 9. Toxicol Sci. 2012. PMID: 22157355

3

Exploiting Pharmacological Similarity to Identify Safety Concerns - Listen to What the Data Tells You.

Muthas D, Boyer S. Muthas D, et al. Mol Inform. 2013 Jan;32(1):37-45. doi: 10.1002/minf.201200088. Epub 2013 Jan 14. Mol Inform. 2013. PMID: 27481022

4

Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes.

Garside H, Marcoe KF, Chesnut-Speelman J, Foster AJ, Muthas D, Kenna JG, Warrior U, Bowes J, Baumgartner J. Garside H, et al. Among authors: muthas d. Toxicol In Vitro. 2014 Mar;28(2):171-81. doi: 10.1016/j.tiv.2013.10.015. Epub 2013 Nov 1. Toxicol In Vitro. 2014. PMID: 24189122 Free article.

5

Is it possible to increase hit rates in structure-based virtual screening by pharmacophore filtering? An investigation of the advantages and pitfalls of post-filtering.

Muthas D, Sabnis YA, Lundborg M, Karlén A. Muthas D, et al. J Mol Graph Model. 2008 Jun;26(8):1237-51. doi: 10.1016/j.jmgm.2007.11.005. Epub 2007 Nov 29. J Mol Graph Model. 2008. PMID: 18203638

6

Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II.

Muthas D, Nöteberg D, Sabnis YA, Hamelink E, Vrang L, Samuelsson B, Karlén A, Hallberg A. Muthas D, et al. Bioorg Med Chem. 2005 Sep 15;13(18):5371-90. doi: 10.1016/j.bmc.2005.06.048. Bioorg Med Chem. 2005. PMID: 16054370

7

Design, synthesis and evaluation of peptide inhibitors of Mycobacterium tuberculosis ribonucleotide reductase.

Nurbo J, Roos AK, Muthas D, Wahlström E, Ericsson DJ, Lundstedt T, Unge T, Karlén A. Nurbo J, et al. Among authors: muthas d. J Pept Sci. 2007 Dec;13(12):822-32. doi: 10.1002/psc.906. J Pept Sci. 2007. PMID: 17918768

8

Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

Odell LR, Nilsson MT, Gising J, Lagerlund O, Muthas D, Nordqvist A, Karlén A, Larhed M. Odell LR, et al. Among authors: muthas d. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4790-3. doi: 10.1016/j.bmcl.2009.06.045. Epub 2009 Jun 14. Bioorg Med Chem Lett. 2009. PMID: 19560924

9

Identification of small peptides mimicking the R2 C-terminus of Mycobacterium tuberculosis ribonucleotide reductase.

Ericsson DJ, Nurbo J, Muthas D, Hertzberg K, Lindeberg G, Karlén A, Unge T. Ericsson DJ, et al. Among authors: muthas d. J Pept Sci. 2010 Mar;16(3):159-64. doi: 10.1002/psc.1214. J Pept Sci. 2010. PMID: 20127854

10

Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic--targeting Mycobacterium tuberculosis ribonucleotide reductase.

Nurbo J, Ericsson DJ, Rosenström U, Muthas D, Jansson AM, Lindeberg G, Unge T, Karlén A. Nurbo J, et al. Among authors: muthas d. Bioorg Med Chem. 2013 Apr 1;21(7):1992-2000. doi: 10.1016/j.bmc.2013.01.020. Epub 2013 Jan 18. Bioorg Med Chem. 2013. PMID: 23395111

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

28 results

Search Page

Filters