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Page 1
Highly specific changes in antioxidant levels and lipid peroxidation in Parkinson's disease and its progression: Disease and staging biomarkers and new drug targets.
de Farias CC, Maes M, Bonifácio KL, Bortolasci CC, de Souza Nogueira A, Brinholi FF, Matsumoto AK, do Nascimento MA, de Melo LB, Nixdorf SL, Lavado EL, Moreira EG, Barbosa DS. de Farias CC, et al. Among authors: bonifacio kl. Neurosci Lett. 2016 Mar 23;617:66-71. doi: 10.1016/j.neulet.2016.02.011. Epub 2016 Feb 6. Neurosci Lett. 2016. PMID: 26861200 Free article.
Parkinson's Disease is Accompanied by Intertwined Alterations in Iron Metabolism and Activated Immune-inflammatory and Oxidative Stress Pathways.
de Farias CC, Maes M, Bonifacio KL, Matsumoto AK, Bortolasci CC, Nogueira AS, Brinholi FF, Morimoto HK, de Melo LB, Moreira EG, Barbosa DS. de Farias CC, et al. Among authors: bonifacio kl. CNS Neurol Disord Drug Targets. 2017;16(4):484-491. doi: 10.2174/1871527316666170223161004. CNS Neurol Disord Drug Targets. 2017. PMID: 28240188
Oxidative and nitrosative stress biomarkers in chronic schizophrenia.
Boll KM, Noto C, Bonifácio KL, Bortolasci CC, Gadelha A, Bressan RA, Barbosa DS, Maes M, Moreira EG. Boll KM, et al. Among authors: bonifacio kl. Psychiatry Res. 2017 Jul;253:43-48. doi: 10.1016/j.psychres.2017.03.038. Epub 2017 Mar 21. Psychiatry Res. 2017. PMID: 28346888
Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses.
Maes M, Bonifacio KL, Morelli NR, Vargas HO, Moreira EG, St Stoyanov D, Barbosa DS, Carvalho AF, Nunes SOV. Maes M, et al. Among authors: bonifacio kl. Neurotox Res. 2018 Oct;34(3):489-510. doi: 10.1007/s12640-018-9906-2. Epub 2018 May 7. Neurotox Res. 2018. PMID: 29736827
Lowered paraoxonase 1 (PON1) activity is associated with increased cytokine levels in drug naïve first episode psychosis.
Brinholi FF, Noto C, Maes M, Bonifácio KL, Brietzke E, Ota VK, Gadelha A, Cordeiro Q, Belangero SI, Bressan RA, Vargas HO, Higachi L, de Farias CC, Moreira EG, Barbosa DS. Brinholi FF, et al. Among authors: bonifacio kl. Schizophr Res. 2015 Aug;166(1-3):225-30. doi: 10.1016/j.schres.2015.06.009. Epub 2015 Jun 27. Schizophr Res. 2015. PMID: 26123170
Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life.
Moreira EG, Correia DG, Bonifácio KL, Moraes JB, Cavicchioli FL, Nunes CS, Nunes SOV, Vargas HO, Barbosa DS, Maes M. Moreira EG, et al. Among authors: bonifacio kl. World J Biol Psychiatry. 2019 Jun;20(5):368-380. doi: 10.1080/15622975.2017.1322219. Epub 2017 May 30. World J Biol Psychiatry. 2019. PMID: 28441923
In major affective disorders, early life trauma predict increased nitro-oxidative stress, lipid peroxidation and protein oxidation and recurrence of major affective disorders, suicidal behaviors and a lowered quality of life.
Moraes JB, Maes M, Roomruangwong C, Bonifacio KL, Barbosa DS, Vargas HO, Anderson G, Kubera M, Carvalho AF, Nunes SOV. Moraes JB, et al. Among authors: bonifacio kl. Metab Brain Dis. 2018 Aug;33(4):1081-1096. doi: 10.1007/s11011-018-0209-3. Epub 2018 Mar 14. Metab Brain Dis. 2018. PMID: 29542039
25 results