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Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
Gomes PA, Oliveira AR, Cardoso MV, Santiago Ede F, Barbosa Mde O, de Siqueira LR, Moreira DR, Bastos TM, Brayner FA, Soares MB, Mendes AP, de Castro MC, Pereira VR, Leite AC. Gomes PA, et al. Among authors: brayner fa. Eur J Med Chem. 2016 Mar 23;111:46-57. doi: 10.1016/j.ejmech.2016.01.010. Epub 2016 Jan 11. Eur J Med Chem. 2016. PMID: 26854377
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles.
Santiago Ede F, de Oliveira SA, de Oliveira Filho GB, Moreira DR, Gomes PA, da Silva AL, de Barros AF, da Silva AC, Dos Santos TA, Pereira VR, Gonçalves GG, Brayner FA, Alves LC, Wanderley AG, Leite AC. Santiago Ede F, et al. Among authors: brayner fa. Antimicrob Agents Chemother. 2014;58(1):352-63. doi: 10.1128/AAC.01900-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165185 Free PMC article.
Phthalimido-thiazole as privileged scaffold: activity against immature and adult worms of Schistosoma mansoni.
de Oliveira SA, de Oliveira Barbosa M, Filho CALM, Oliveira AR, de Sousa FA, de Farias Santiago E, de Oliveira Filho GB, de Moraes Gomes PAT, da Conceição JM, Brayner FA, Alves LC, Leite ACL. de Oliveira SA, et al. Among authors: brayner fa. Parasitol Res. 2018 Jul;117(7):2105-2115. doi: 10.1007/s00436-018-5897-4. Epub 2018 May 7. Parasitol Res. 2018. PMID: 29736731
Schistosomicidal and prophylactic activities of phthalimido-thiazoles derivatives on schistosomula and adult worms.
de Oliveira Barbosa M, de Oliveira SA, Filho CALM, Oliveira AR, Fernandes CJB, Lucena JP, de Sousa FA, de Barros Dias MCH, Brayner FA, Alves LC, Leite ACL. de Oliveira Barbosa M, et al. Among authors: brayner fa. Eur J Pharm Sci. 2019 May 15;133:15-27. doi: 10.1016/j.ejps.2019.03.008. Epub 2019 Mar 12. Eur J Pharm Sci. 2019. PMID: 30877068
Thiophene-thiosemicarbazone derivative (L10) exerts antifungal activity mediated by oxidative stress and apoptosis in C. albicans.
de Araújo Neto LN, de Lima MDCA, de Oliveira JF, de Souza ER, Feitosa Machado SE, de Souza Lima GM, Silva Buonafina MD, Brayner FA, Alves LC, Sandes JM, da Silva MV, de Castro MCAB, Pereira Neves R, Bezerra Mendonça-Junior FJ. de Araújo Neto LN, et al. Among authors: brayner fa. Chem Biol Interact. 2020 Apr 1;320:109028. doi: 10.1016/j.cbi.2020.109028. Epub 2020 Feb 28. Chem Biol Interact. 2020. PMID: 32119865 Free article.
Dual Parasiticidal Activities of Phthalimides: Synthesis and Biological Profile against Trypanosoma cruzi and Plasmodium falciparum.
Teixeira de Moraes Gomes PA, Veríssimo de Oliveira Cardoso M, Dos Santos IR, Amaro de Sousa F, da Conceição JM, Gouveia de Melo Silva V, Duarte D, Pereira R, Oliveira R, Nogueira F, Alves LC, Brayner FA, da Silva Santos AC, Rêgo Alves Pereira V, Lima Leite AC. Teixeira de Moraes Gomes PA, et al. Among authors: brayner fa. ChemMedChem. 2020 Nov 18;15(22):2164-2175. doi: 10.1002/cmdc.202000331. Epub 2020 Oct 19. ChemMedChem. 2020. PMID: 32813331
Structural design, synthesis and anti-Trypanosoma cruzi profile of the second generation of 4-thiazolidinones chlorine derivatives.
Bezerra de Oliveira Filho G, Veríssimo de Oliveira Cardoso M, Caroline da Silva Santos A, Ramos Dos Santos TA, Cristovão-Silva AC, Rubio LG, da Silva Maia Neto L, Leite PG, Machado FS, Alves LC, Brayner FA, Alves Pereira VR, Lima Leite AC. Bezerra de Oliveira Filho G, et al. Among authors: brayner fa. Chem Biol Interact. 2021 Aug 25;345:109514. doi: 10.1016/j.cbi.2021.109514. Epub 2021 May 21. Chem Biol Interact. 2021. PMID: 34023282
The design, synthesis, and in vitro trypanocidal and leishmanicidal activities of 1,3-thiazole and 4-thiazolidinone ester derivatives.
Haroon M, de Barros Dias MCH, Santos ACDS, Pereira VRA, Barros Freitas LA, Balbinot RB, Kaplum V, Nakamura CV, Alves LC, Brayner FA, Leite ACL, Akhtar T. Haroon M, et al. Among authors: brayner fa. RSC Adv. 2021 Jan 11;11(4):2487-2500. doi: 10.1039/d0ra06994a. eCollection 2021 Jan 6. RSC Adv. 2021. PMID: 35424158 Free PMC article.
Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones.
Conceição JMD, Santos ACDS, Brayner FA, Alves LC, Pinto AF, Brondani GL, Oliveira Filho GB, Bedor DCG, Silva JWVD, Sales Junior PA, Cavalcante MKA, Silva EDD, Pereira VRA, Leite ACL. Conceição JMD, et al. Among authors: brayner fa. Eur J Med Chem. 2023 Jun 5;254:115310. doi: 10.1016/j.ejmech.2023.115310. Epub 2023 Apr 6. Eur J Med Chem. 2023. PMID: 37062170
99 results