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Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.
Zick A, Peretz T, Lotem M, Hubert A, Katz D, Temper M, Rottenberg Y, Uziely B, Nechushtan H, Meirovitz A, Sonnenblick A, Sapir E, Edelman D, Goldberg Y, Lossos A, Rosenberg S, Fried I, Finklstein R, Pikarsky E, Goldshmidt H. Zick A, et al. Among authors: hubert a. Medicine (Baltimore). 2017 May;96(20):e6931. doi: 10.1097/MD.0000000000006931. Medicine (Baltimore). 2017. PMID: 28514312 Free PMC article.
Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics.
Fedyuk V, Erez N, Furth N, Beresh O, Andreishcheva E, Shinde A, Jones D, Zakai BB, Mavor Y, Peretz T, Hubert A, Cohen JE, Salah A, Temper M, Grinshpun A, Maoz M, Zick A, Ron G, Shema E. Fedyuk V, et al. Among authors: hubert a. Nat Biotechnol. 2023 Feb;41(2):212-221. doi: 10.1038/s41587-022-01447-3. Epub 2022 Sep 8. Nat Biotechnol. 2023. PMID: 36076083
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
Goldberg Y, Porat RM, Kedar I, Shochat C, Galinsky D, Hamburger T, Hubert A, Strul H, Kariiv R, Ben-Avi L, Savion M, Pikarsky E, Abeliovich D, Bercovich D, Lerer I, Peretz T. Goldberg Y, et al. Among authors: hubert a. Fam Cancer. 2010 Jun;9(2):141-50. doi: 10.1007/s10689-009-9298-9. Fam Cancer. 2010. PMID: 19851887
Phenotypic characteristics of colorectal cancer in BRCA1/2 mutation carriers.
Grinshpun A, Halpern N, Granit RZ, Hubert A, Hamburger T, Laitman Y, Shacham-Shmueli E, Peerless Y, Friedman E, Peretz T. Grinshpun A, et al. Among authors: hubert a. Eur J Hum Genet. 2018 Mar;26(3):382-386. doi: 10.1038/s41431-017-0067-1. Epub 2018 Jan 10. Eur J Hum Genet. 2018. PMID: 29321669 Free PMC article.
ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin.
Sadeh R, Sharkia I, Fialkoff G, Rahat A, Gutin J, Chappleboim A, Nitzan M, Fox-Fisher I, Neiman D, Meler G, Kamari Z, Yaish D, Peretz T, Hubert A, Cohen JE, Salah A, Temper M, Grinshpun A, Maoz M, Abu-Gazala S, Ben Ya'acov A, Shteyer E, Safadi R, Kaplan T, Shemer R, Planer D, Galun E, Glaser B, Zick A, Dor Y, Friedman N. Sadeh R, et al. Among authors: hubert a. Nat Biotechnol. 2021 May;39(5):586-598. doi: 10.1038/s41587-020-00775-6. Epub 2021 Jan 11. Nat Biotechnol. 2021. PMID: 33432199 Free PMC article.
320 results